Evidence map›Paper›PMID 33150329›Full record

ArticleEClinicalMedicine2020

The hepatitis C virus care cascade in the New York City jail system during the direct acting antiviral treatment era, 2014-2017.

Justin Chan, Fatos Kaba, Jessie Schwartz, Angelica Bocour, Matthew J Akiyama, Zachary Rosner, Ann Winters, Patricia Yang, Ross MacDonald

Abstract read
In one paragraph

Article in EClinicalMedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Hepatitis C Cascades: Data to Inform Hepatitis C Elimination in the United States.Public health reports (Washington, D.C. : 1974) · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Justin ChanCorrectional Health Services, NYC Health + Hospitals, 55 Water Street, 18th floor, New York, NY 10041, United States.
Fatos KabaCorrectional Health Services, NYC Health + Hospitals, 55 Water Street, 18th floor, New York, NY 10041, United States.
Jessie SchwartzBureau of Communicable Diseases, Viral Hepatitis Program, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, United States.
Angelica BocourBureau of Communicable Diseases, Viral Hepatitis Program, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, United States.
Matthew J AkiyamaMontefiore Medical Center, Albert Einstein College of Medicine, 1621 Eastchester Road, Bronx, NY 10461, United States.
Zachary RosnerCorrectional Health Services, NYC Health + Hospitals, 55 Water Street, 18th floor, New York, NY 10041, United States.
Ann WintersBureau of Communicable Diseases, Viral Hepatitis Program, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, United States.
Patricia YangCorrectional Health Services, NYC Health + Hospitals, 55 Water Street, 18th floor, New York, NY 10041, United States.
Ross MacDonaldCorrectional Health Services, NYC Health + Hospitals, 55 Water Street, 18th floor, New York, NY 10041, United States.

Funding

Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants LivingR00DA043011 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI AKIYAMA, MATTHEW · 2020 to 2022
$747k
NIDA NIH HHS R00 DA043011
6 · The paper itself

Abstract

backgroundHigh patient turnover presents challenges and opportunity to provide hepatitis C virus (HCV) care in US jails (remand facilities). This study describes the HCV care cascade in the New York City (NYC) jail system during the direct-acting antiviral (DAA) treatment era.

methodsPatients admitted to the NYC jail system from January 2014 through December 2017 were included in this retrospective cohort analysis. We describe rates of screening, diagnosis, linkage to jail-based care, and treatment among the overall cohort, and among subgroups with long jail stays (≥120 days) or frequent stays (≥10 admissions). The study protocol was approved by a third-party institutional review board (BRANY, Lake Success, NY).

findingsAmong the 121,371 patients in our analysis, HCV screening was performed in 40,219 (33%), 4665 (12%) of whom were viremic, 1813 (39%) seen by an HCV clinician in jail, and 248 (5% of viremic patients) started on treatment in jail. Having a long stay (adjusted risk ratio [aRR] 8·11, 95% confidence interval [CI] 6·98, 9·42) or frequent stays (aRR 1·51, 95% CI 1·04, 2·18) were significantly associated with being seen by an HCV clinician. Patients with long stays had a higher rate of treatment (14% of viremic patients). Sustained virologic response at 12 weeks was achieved in 147/164 (90%) of patients with available virologic data.

interpretationJail health systems can reach large numbers of HCV-infected individuals. The high burden of HCV argues for universal screening in jail settings. Length of stay was strongly associated with being seen by an HCV clinician in jail. Treatment is feasible among those with longer lengths of stay.

fundingNone.

Indexed as

Care cascadeDirect-acting antiviralHepatitis C virusIncarceratedJail

Identifiers

PMID33150329
PMCPMC7599312

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.