Evidence map›Paper›PMID 33150187›Full record

ArticleJournal of diabetes research2020

Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms.

Wei Liu, Yunchao Zhang, Qi Chen, Su Liu, Weilong Xu, Wenbin Shang, Lijuan Wang, Jiangyi Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  16. Mechanisms of Melatonin in Obesity: A Review.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wei LiuDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0001-7882-3953
Yunchao ZhangDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0001-5477-6793
Qi ChenDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-0670-4397
Su LiuDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0001-8440-8932
Weilong XuDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-2754-6033
Wenbin ShangDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-5224-2576
Lijuan WangDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-4438-5083
Jiangyi YuDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-6791-2069
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern lifestyle-associated factors, such as high-calorie intake, high-fat diet (HFD), and excessive artificial light, are risk factors for glucose and lipid metabolism disturbances. Melatonin may be beneficial for managing obesity and diabetes; however, the underlying molecular mechanisms are not well elucidated. We aimed to assess whether melatonin has beneficial effects on constant artificial light-induced fat deposition, lipid metabolism, and insulin resistance. Guinea pigs were randomly divided into five experimental groups: control (C), HFD (H), 12 h light (12HL), 24 h light (24HL), and melatonin (M). The majority of indexes, including insulin resistance and obesity, were measured after 10 weeks. AMP-activated protein kinase

Indexed as

LightAdipose TissueAMP-Activated Protein KinasesAnimalsBlood GlucoseBody WeightCarnitine O-PalmitoyltransferaseDiet, High-FatFemaleGlucoseGlucose Tolerance TestGuinea PigsInsulin ResistanceLipid MetabolismLipid Metabolism DisordersLiverAMP-Activated Protein KinasesBlood GlucoseCarnitine O-PalmitoyltransferaseCPT1A protein, humanGlucoseMelatoninPhosphatidylinositol 3-KinasesPPAR alphaTriglycerides

Identifiers

PMID33150187
PMCPMC7603608
OpenAlexW3094056791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.