Evidence map›Paper›PMID 33150142›Full record

ArticleResearch and reports in urology2020

Mid-Term Safety and Efficacy of the Modified Double Hydrodistention Implantation Technique (HIT), Termed Systematic Multi-Site HIT (SMHIT), for Patients with Primary Vesicoureteral Reflux.

Shigeru Nakamura, Kazuya Tanabe, Taiju Hyuga, Taro Kubo, Satoru Inoguchi, Shina Kawai, Hideo Nakai

Open access · goldAbstract read
In one paragraph

Article in Research and reports in urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shigeru NakamuraDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.ORCID 0000-0002-3607-5974
Kazuya TanabeDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.
Taiju HyugaDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.
Taro KuboDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.
Satoru InoguchiDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.ORCID 0000-0002-3528-6585
Shina KawaiDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.ORCID 0000-0002-5938-5377
Hideo NakaiDepartment of Pediatric Urology, Jichi Medical University, Children's Medical Center Tochigi, Shimotsuke, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the treatment outcomes and postoperative complications associated with the systematic multi-site hydrodistention implantation technique (SMHIT) for primary vesicoureteral reflux (VUR) and to determine its mid-term efficacy and safety. PATIENTS AND

methodsWe retrospectively reviewed the data for 17 ureters from 12 consecutive children, aged ≥1 year, with grade II-IV reflux and a history of febrile urinary tract infections (FUTI), who underwent a single-session of SMHIT. The primary outcome was the absence of postoperative FUTI (clinical success). The secondary outcome was improvement in reflux to grade 0-I on postoperative voiding cystourethrography (radiographic success).

resultsFive and 7 children had bilateral and unilateral reflux, respectively. Reflux was categorized as grade II, III, and IV reflux in 2, 12, and 3 ureters, respectively. Seven of 10 (70%) toilet-trained children had bladder-bowel dysfunction (BBD) preoperatively. The SMHIT was performed for all patients, after which BBD improved. The mean postoperative follow-up period was 6 years and 9 months. The clinical success rate was 100%. Radiographic success was achieved in 16/17 ureters (94%) at 3-4 months, 17/17 (100%) ureters at 1 year, and 17/17 (100%) ureters at 3 years postoperatively. Major complications did not develop postoperatively.

conclusionWhen prioritizing treatment of concomitant BBD in children with primary VUR and avoiding dextranomer/hyaluronic acid injection therapy in contraindicated children according to the Food and Drug Administration recommendations, a single-session of SMHIT may be as effective and safe in the mid-term as performing open anti-reflux surgery.

Indexed as

dextranomer hyaluronic acidDx/HAendoscopic treatmentvesicoureteral reflux

Identifiers

PMID33150142
PMCPMC7604468
OpenAlexW3094748901

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