ArticleGlobal heart2020
Age and Sex Differences in Heart Rate Variability and Vagal Specific Patterns - Baependi Heart Study.
Article in Global heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Heart Rate Variability and Heart Failure with Reduced Ejection Fraction: A Systematic Review of Literature.Current cardiology reviews · 2025Pooled it
- Day and night heart rate variability using 24-h ECG recordings: a systematic review with meta-analysis using a gender lens.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Pooled it
- Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults.Scientific reports · 2021Trial
- Cumulative trauma exposure and cardiac autonomic stress reactivity in healthy adults.European journal of psychotraumatology · 2026Article
- Pre-induction nociception indices are associated with post-induction hypotension during general anesthesia in older patients: a prospective observational study.Journal of clinical monitoring and computing · 2026Observational
- Temporal dissociation between heart rate recovery and heart rate variability recovery after submaximal exercise in healthy older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- Using Passive Sensing to Isolate a Biosignature for Craving Among Individuals in Early Alcohol Use Disorder Recovery.Addiction biology · 2026Article
- Circadian rhythm of heart rate variability in tropical horses: age-associated autonomic alterations and environmental air pollution effects in an urban field setting.Veterinary world · 2026Article
- Effects on 24-h physical behaviors and heart rate variability during sleep of a co-created workplace intervention to promote recovery in office workers with flexible work.Journal of activity, sedentary and sleep behaviors · 2026Article
- Heart Rate Variability and Body Motion as Digital Biomarkers of Task Workload During Military En Route Critical Care Simulations.Sensors (Basel, Switzerland) · 2026Article
- Intraoperative text messaging to reduce parental stress during outpatient pediatric surgery: a randomized trial.Pediatric research · 2026Article
- Cognitive biotypes identified through ECG-derived workload and behavioral accuracy.Scientific reports · 2026Article
- Article
- Interpreting heart rate variability in clinical context: a framework for understanding a multidimensional autonomic biomarker.Frontiers in cardiovascular medicine · 2026Review
- Short-term atrial fibrillation onset prediction using machine learning.European heart journal. Digital health · 2025Article
- Factors influencing heart rate variability in nurses following night shifts: a prospective observational clinical study.BMC nursing · 2025Article
- Short-term association between ambient air pollution and heart rate variability: results from the population-based KORA S4 and FF4 studies.Particle and fibre toxicology · 2025Article
- Resting HRV Sample Entropy Predicts the Magnitude of Post-Exercise Vagal Withdrawal in Young Adults.Medicina (Kaunas, Lithuania) · 2025Article
- An infection prediction model developed from inpatient data can predict out-of-hospital COVID-19 infections from wearable data when controlled for dataset shift.Scientific reports · 2025Article
- Changes in Autonomic Balance, Cardiac Parasympathetic Modulation, and Cardiac Baroreflex Gain in Older Adults Under Different Orthostatic Stress Conditions.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart rate variability (HRV) is a noninvasive method for assessing autonomic function. Age, sex, and chronic conditions influence HRV. Objectives: Our aim was to evaluate HRV measures exploring differences by age, sex, and race in a sample from a rural area. Methods: Analytical sample (n = 1,287) included participants from the 2010 to 2016 evaluation period of the Baependi Heart Study, a family-based cohort in Brazil. Participants underwent 24-hour Holter-ECG (Holter) monitoring. To derive population reference values, we restricted our analysis to a 'healthy' subset (i.e. absence of medical comorbidities). A confirmatory analysis was conducted with a subgroup sample that also had HRV derived from a resting ECG 10'-protocol obtained during the same time period. Results: The 'healthy' subset included 543 participants. Mean age was 40 ± 14y, 41% were male, 74% self-referred as white and mean body-mass-index was 24 ± 3kg/m Conclusion: HRV measures vary across age and sex. A U-shaped pattern and a reversal increase in parasympathetic variables may reflect an age-related autonomic dysfunction even in healthy individuals that could be used as a predictor of disease development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.