ArticleBiomedical optics express2020
Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Phase-based optoretinographic measurements of cones with a raster-scanning adaptive optics OCT are highly repeatable.Biomedical optics express · 2026Article
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- Insight into human photoreceptor function: Modeling optoretinographic responses to diverse stimuli.Science advances · 2025Article
- Phase-restoring subpixel image registration: enhancing motion detection performance in Fourier-domain optical coherence tomography.Journal of physics D: Applied physics · 2025Article
- Investigating the impact of different time delays between OCT signal and k-clock signal on the structural and vascular imaging in SS-OCT.Biomedical optics express · 2025Article
- Aberration compensation in Doppler holography of the human eye fundus by subaperture signal correlation.Biomedical optics express · 2024Article
- On-axis full-field swept-source optical coherence tomography for murine retinal imaging.Optics letters · 2024Article
- 828 kHz retinal imaging with an 840 nm Fourier domain mode locked laser.Biomedical optics express · 2023Article
- Correcting spatial-spectral crosstalk and chromatic aberrations in broadband line-scan spectral-domain OCT images.Biomedical optics express · 2023Article
- Fractal-based aberration-corrected full-field OCT.Biomedical optics express · 2023Article
- Evolution of adaptive optics retinal imaging [Invited].Biomedical optics express · 2023Review
- Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina.Biomedical optics express · 2022Article
- The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques.Frontiers in medicine · 2022Review
- Simultaneous directional full-field OCT using path-length and carrier multiplexing.Optics express · 2021Article
- Reflective mirror-based line-scan adaptive optics OCT for imaging retinal structure and function.Biomedical optics express · 2021Article
- Toward a clinical optoretinogram: a review of noninvasive, optical tests of retinal neural function.Annals of translational medicine · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A retinal imaging system was designed for full-field (FF) swept-source (SS) optical coherence tomography (OCT) with cellular resolution. The system incorporates a real-time adaptive optics (AO) subsystem and a very high-speed CMOS sensor, and is capable of acquiring volumetric images of the retina at rates up to 1 kHz. While digital aberration correction (DAC) is an attractive potential alternative to AO, it has not yet been shown to provide resolution allowing visualization of cones in the fovea, where early detection of functional deficits is most critical. Here we demonstrate that FF-SS-OCT with hardware AO permits resolution of foveal cones, imaged at eccentricities of 1° and 2°, with volume rates adequate to measure light-evoked changes in photoreceptors. With the reference arm blocked, the system can operate as a kilohertz AO flood illumination fundus camera with adjustable temporal coherence and is expected to allow measurement of light-evoked changes caused by common path interference in photoreceptor outer segments (OS). In this paper, we describe the system's optical design, characterize its performance, and demonstrate its ability to produce images of the human photoreceptor mosaic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.