Evidence map›Paper›PMID 33149980›Full record

ArticleBiomedical optics express2020

Real-time, wide-field and high-quality single snapshot imaging of optical properties with profile correction using deep learning.

Enagnon Aguénounon, Jason T Smith, Mahdi Al-Taher, Michele Diana, Xavier Intes, Sylvain Gioux

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  7. Review
  8. Article
  9. Relevance and utility of theBiomedical optics express · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Deep learning in optical metrology: a review.Light, science & applications · 2022
    Review
  17. Deep learning in macroscopic diffuse optical imaging.Journal of biomedical optics · 2022
    Review
  18. Article
  19. Biomedical optics express · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Enagnon AguénounonUniversity of Strasbourg, ICube Laboratory, 300 Boulevard Sébastien Brant, 67412 Illkirch, France.
Jason T SmithDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Mahdi Al-TaherInstitute of Image-Guided Surgery, IHU Strasbourg, Strasbourg, France.
Michele DianaUniversity of Strasbourg, ICube Laboratory, 300 Boulevard Sébastien Brant, 67412 Illkirch, France.
Xavier IntesDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.ORCID https://orcid.org/0000-0001-5868-4845
Sylvain GiouxUniversity of Strasbourg, ICube Laboratory, 300 Boulevard Sébastien Brant, 67412 Illkirch, France.

Funding

Role of tumor heterogeneity on receptor engagementR01CA207725 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, CORR, DAVID THOMAS · 2017 to 2021
$3.0M
In vivo Macroscopic Fluorescence Lifetime Molecular Optical ImagingR01CA250636 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2020 to 2023
$2.9M
Photon-counting X-ray and Optical Tomography for Preclinical Cancer ResearchR01CA237267 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2019 to 2023
$2.9M
6 · The paper itself

Abstract

The development of real-time, wide-field and quantitative diffuse optical imaging methods to visualize functional and structural biomarkers of living tissues is a pressing need for numerous clinical applications including image-guided surgery. In this context, Spatial Frequency Domain Imaging (SFDI) is an attractive method allowing for the fast estimation of optical properties using the Single Snapshot of Optical Properties (SSOP) approach. Herein, we present a novel implementation of SSOP based on a combination of deep learning network at the filtering stage and Graphics Processing Units (GPU) capable of simultaneous high visual quality image reconstruction, surface profile correction and accurate optical property (OP) extraction in real-time across large fields of view. In the most optimal implementation, the presented methodology demonstrates megapixel profile-corrected OP imaging with results comparable to that of profile-corrected SFDI, with a processing time of 18 ms and errors relative to SFDI method less than 10% in both profilometry and profile-corrected OPs. This novel processing framework lays the foundation for real-time multispectral quantitative diffuse optical imaging for surgical guidance and healthcare applications. All code and data used for this work is publicly available at www.healthphotonics.org under the resources tab.

Identifiers

PMID33149980
PMCPMC7587245

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.