Evidence map›Paper›PMID 33149968›Full record

ArticleBiomedical optics express2020

Three-dimensional collagen fiber mapping and tractography of human uterine tissue using OCT.

James P McLean, Shuyang Fang, George Gallos, Kristin M Myers, Christine P Hendon

Abstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  13. Deep Learning in Biomedical Optics.Lasers in surgery and medicine · 2021
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James P McLeanDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA.ORCID https://orcid.org/0000-0002-8302-108X
Shuyang FangDepartment of Mechanical Engineering, Columbia University, New York, NY 10027, USA.
George GallosDepartment of Anesthesiology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Kristin M MyersDepartment of Mechanical Engineering, Columbia University, New York, NY 10027, USA.
Christine P HendonDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA.

Funding

High resolution imaging of the myocardiumDP2HL127776 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENDON, CHRISTINE P · 2014 to 2019
$2.9M
Calcium activated chloride channel modulation of myometrial excitabilityR01HD082251 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EMALA, CHARLES W · 2016 to 2020
$1.6M
A Computational Framework for the Clinical Evaluation of the Soft Tissue Mechanics in PregnancyR01HD091153 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI MYERS, KRISTIN MARIE · 2017 to 2021
$1.6M
NHLBI NIH HHS DP2 HL127776NICHD NIH HHS R01 HD082251NICHD NIH HHS R01 HD091153
6 · The paper itself

Abstract

Automatic quantification and visualization of 3-D collagen fiber architecture using Optical Coherence Tomography (OCT) has previously relied on polarization information and/or prior knowledge of tissue-specific fiber architecture. This study explores image processing, enhancement, segmentation, and detection algorithms to map 3-D collagen fiber architecture from OCT images alone. 3-D fiber mapping, histogram analysis, and 3-D tractography revealed fiber groupings and macro-organization previously unseen in uterine tissue samples. We applied our method on centimeter-scale mosaic OCT volumes of uterine tissue blocks from pregnant and non-pregnant specimens revealing a complex, patient-specific network of fibrous collagen and myocyte bundles.

Identifiers

PMID33149968
PMCPMC7587264

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.