Evidence map›Paper›PMID 33149961›Full record

ArticleBiomedical optics express2020

Spatial frequency domain imaging for the longitudinal monitoring of vascularization during mouse femoral graft healing.

Jingxuan Ren, Gabriel A Ramirez, Ashley R Proctor, Tong Tong Wu, Danielle S W Benoit, Regine Choe

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jingxuan RenDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID https://orcid.org/0000-0002-0020-1211
Gabriel A RamirezDepartment of Orthopaedics and Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA.
Ashley R ProctorDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.
Tong Tong WuDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.
Danielle S W BenoitDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID https://orcid.org/0000-0001-7137-8164
Regine ChoeDepartment of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.ORCID https://orcid.org/0000-0001-5851-4504
University of Rochester · US

Funding

Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
Tissue Engineering Strategies to Revitalize Bone AllograftsR01AR064200 · NIAMS · UNIVERSITY OF ROCHESTER · PI Danielle S. Benoit · 2013 to 2026
$4.0M
Longitudinal monitoring of bone fracture healing using diffuse optical and correlation tomographyR01AR071363 · NIAMS · UNIVERSITY OF ROCHESTER · PI REGINE CHOE · 2017 to 2026
$2.2M
NIAMS NIH HHS P30 AR069655NIAMS NIH HHS R01 AR064200NIAMS NIH HHS R01 AR071363
6 · The paper itself

Abstract

Allograft is the current gold standard for treating critical-sized bone defects. However, allograft healing is usually compromised partially due to poor host-mediated vascularization. In the efforts towards developing new methods to enhance allograft healing, a non-terminal technique for monitoring the vascularization is needed in pre-clinical mouse models. In this study, we developed a non-invasive instrument based on spatial frequency domain imaging (SFDI) for longitudinal monitoring of the mouse femoral graft healing. SFDI technique provided total hemoglobin concentration (THC) and oxygen saturation (StO

Identifiers

PMID33149961
PMCPMC7587272
OpenAlexW3081112465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.