Evidence map›Paper›PMID 33149924›Full record

ReviewCanadian journal of kidney health and disease2020

A Comparison of Patient-Reported Outcome Measures of Quality of Life By Dialysis Modality in the Treatment of Kidney Failure: A Systematic Review.

Brandon Budhram, Alison Sinclair, Paul Komenda, Melissa Severn, Manish M Sood

Open access · goldAbstract readReview
In one paragraph

Review in Canadian journal of kidney health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Dialysis and cognitive impairment.Nature reviews. Nephrology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Patient perspectives on peritoneal dialysis (PD) and the PD catheter: Strategies and Solutions.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2023
    Article
  13. Article
  14. Transitions between dialysis modalities.Journal of nephrology · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Automated Peritoneal Dialysis: Patient Perspectives and Outcomes.International journal of nephrology and renovascular disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brandon BudhramThe Ottawa Hospital Research Institute, The Ottawa Hospital, ON, Canada.
Alison SinclairCanadian Agency for Drugs and Technologies in Health, Ottawa, ON, Canada.
Paul KomendaSeven Oaks General Hospital, Winnipeg, MB, Canada.
Melissa SevernCanadian Agency for Drugs and Technologies in Health, Ottawa, ON, Canada.
Manish M SoodThe Ottawa Hospital Research Institute, The Ottawa Hospital, ON, Canada.ORCID https://orcid.org/0000-0002-9146-2344
Canadian Agency for Drugs and Technologies in Health · CAOttawa Hospital · CASeven Oaks General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is an increasing demand to incorporate patient-reported outcome measures (PROMs) such as quality of life (QOL) in decision-making when selecting a chronic dialysis modality.

objectiveTo compare the change in QOL over time among similar patients on different dialysis modalities to provide unique and novel insights on the impact of dialysis modality on PROMs.

designSystematic reviews, randomized controlled trials, and nonrandomized controlled trials were examined via a comprehensive search strategy incorporating multiple bibliographic databases.

settingData were extracted from relevant studies from January 1, 2000 to December 31, 2019 without limitations on country of study conduction. PATIENTS: Eligible studies included adults (≥18 years) with end-stage kidney disease of any cause who were prescribed dialysis treatment (either as lifetime treatment or bridge to transplant). MEASUREMENTS: The 5 comparisons were peritoneal dialysis (PD) vs in-center hemodialysis (ICHD), home hemodialysis (HHD) vs ICHD, HHD modalities compared with one another, HHD vs PD, and self-care ICHD vs traditional nurse-based ICHD.

methodsIncluded studies compared adults on different dialysis modalities with repeat measures within individuals to determine changes in QOL between dialysis modalities (in-center or home dialysis). Methodological quality was assessed by the Scottish Intercollegiate Guidelines Network (SIGN 50) checklist. A narrative synthesis was conducted, synthesizing the direction and size of any observed effects across studies.

resultsTwo randomized controlled trials and 9 prospective cohort studies involving a combined total of 3711 participants were included. Comparing PD and ICHD, 5 out of 9 studies found significant differences ( LIMITATIONS: Our study is constrained by the small sample sizes of included studies, as well as heterogeneity among both study populations and validated QOL scales, limiting inter-study comparison.

conclusionsWe identified differences in specific QOL domains between dialysis modalities that may aid in patient decision-making based on individual priorities.

trial registrationPROSPERO Registration Number: CRD42016046980. PRIMARY FUNDING SOURCE: The original research for this study was derived from the Canadian Agency for Drugs and Technologies in Health (CADTH) 2017 optimal use report, titled "Dialysis Modalities for the Treatment of End-Stage Kidney Disease: A Health Technology Assessment." The CADTH receives funding from Canada's federal, provincial, and territorial governments, with the exception of Quebec.

Indexed as

dialysisdialysis choicehealth-related quality of lifeperitoneal dialysisquality of life

Identifiers

PMID33149924
PMCPMC7580133
OpenAlexW3094460539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.