Evidence map›Paper›PMID 33149810›Full record

ArticleOxidative medicine and cellular longevity2020

MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model.

Qingmin Sun, Jingwen Chen, Lizhi Xu, Jiaqi Kang, Xin Wu, Yan Ren, Yusaku Nakabeppu, Yaping Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Qingmin SunDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.ORCID https://orcid.org/0000-0002-4428-4637
Jingwen ChenDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.
Lizhi XuDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.
Jiaqi KangDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.
Xin WuDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.
Yan RenDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.
Yusaku NakabeppuDivision of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.ORCID https://orcid.org/0000-0002-6739-242X
Yaping WangDepartment of Medical Genetics, Nanjing University School of Medicine, Nanjing 210093, China.ORCID https://orcid.org/0000-0002-4948-8970
Nanjing Medical University · CNKyushu University · JPNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible lung disease of unknown etiology with limited survival. IPF incidence and prevalence increase significantly with aging, which is associated with an age-related accumulation of oxidative DNA damage. The

Indexed as

A549 CellsAnimalsApoptosisBiomarkersBleomycinDisease Models, AnimalDNA Breaks, Single-StrandedDNA GlycosylasesDNA, MitochondrialEpithelial CellsGuanineHomeostasisHumansIdiopathic Pulmonary FibrosisLungMice, Inbred C57BL8-hydroxyguanineBiomarkersBleomycinDNA GlycosylasesDNA, MitochondrialGuaninemutY adenine glycosylaseTransforming Growth Factor beta1

Identifiers

PMID33149810
PMCPMC7603627
OpenAlexW3094509446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.