Evidence map›Paper›PMID 33149757›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Cardiac CaMKII

Na An, Yu Chen, Yanfen Xing, Honghua Wu, Xiongyi Gao, Hengwen Chen, Ke Song, Yuanyuan Li, Xinye Li, Fan Yang and 6 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Na An *Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Yu Chen *Fujian Health College, Fuzhou 350101, China.
Yanfen Xing *Shanxi University of Chinese Medicine, Jinzhong 030619, China.
Honghua Wu *Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of TCM Chemistry and Analysis Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Xiongyi GaoGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Hengwen ChenGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Ke SongKey Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.
Yuanyuan LiKey Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.
Xinye LiGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Fan YangGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Xiandu PanGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.
Xiaofang HeKey Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.
Xin WangKey Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.
Yang LiDepartment of Cardiology, General Hospital of People's Liberation Army, Beijing 100853, China.
Yonghong GaoKey Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China.ORCID https://orcid.org/0000-0002-3771-3528
Yanwei XingGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China.ORCID https://orcid.org/0000-0002-1392-9738
Chinese Academy of Medical Sciences & Peking Union Medical College · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNBeijing University of Chinese Medicine · CNPeople's Liberation Army No. 150 Hospital · CNShanxi University · CNBeijing Health Vocational College · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated that calcium-/calmodulin-dependent protein kinase II (CaMKII) and calcineurin A-nuclear factor of activated T-cell (CnA-NFAT) signaling pathways play key roles in cardiac hypertrophy (CH). However, the interaction between CaMKII and CnA-NFAT signaling remains unclear. H9c2 cells were cultured and treated with angiotensin II (Ang II) with or without silenced CaMKII

Identifiers

PMID33149757
PMCPMC7603598
OpenAlexW3094139279

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.