Evidence map›Paper›PMID 33149723›Full record

ArticleMediators of inflammation2020

Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations.

Rayra P Santiago, Camylla V B Figueiredo, Luciana M Fiuza, Sètondji C M A Yahouédéhou, Rodrigo M Oliveira, Milena M Aleluia, Suellen P Carvalho, Cleverson A Fonseca, Valma M L Nascimento, Larissa C Rocha and 2 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Association of Serum Level of TGF-βHealth science reports · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rayra P SantiagoLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-2055-1291
Camylla V B FigueiredoLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-1366-7747
Luciana M FiuzaLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0002-7581-3474
Sètondji C M A YahouédéhouLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-4219-1311
Rodrigo M OliveiraLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0001-9825-9501
Milena M AleluiaDepartamento de Ciências Biológicas, Universidade Estadual de Santa Cruz, UESC, Ilhéus 45662-900, Brazil.ORCID https://orcid.org/0000-0001-6928-824X
Suellen P CarvalhoLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-3756-9252
Cleverson A FonsecaUniversidade Federal da Bahia, UFBA, Salvador 40170-110, Brazil.ORCID https://orcid.org/0000-0002-8251-988X
Valma M L NascimentoFundação de Hematologia e Hemoterapia do Estado da Bahia, HEMOBA, Salvador 40286-240, Brazil.
Larissa C RochaFundação de Hematologia e Hemoterapia do Estado da Bahia, HEMOBA, Salvador 40286-240, Brazil.
Caroline C GuardaLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-1356-8298
Marilda S GonçalvesLaboratório de Investigação em Genética e Hematologia Translacional, Instituto Gonçalo Moniz, FIOCRUZ-BA, Salvador 40296-710, Brazil.ORCID https://orcid.org/0000-0003-3000-1437
Universidade Federal da Bahia · BRUniversidade Estadual de Santa Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-

Indexed as

HaplotypesPolymorphism, Single NucleotideAdolescentAnemia, Sickle CellBiomarkersCell ProliferationChildCholesterolCholesterol, LDLFemaleGenotypeHemoglobinsHumansInflammationLinkage DisequilibriumLipidsbetaglycanBiomarkersCholesterolCholesterol, LDLHemoglobinsLipidsProteoglycansReceptors, Transforming Growth Factor beta

Identifiers

PMID33149723
PMCPMC7603616
OpenAlexW3094448968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.