Evidence map›Paper›PMID 33149566›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2020

Relationship Between Clinical Control, Respiratory Symptoms and Quality of Life for Patients with COPD.

Bernardino Alcazar-Navarrete, Antonia Fuster, Patricia García Sidro, Juan Luis García Rivero, Beatriz Abascal-Bolado, Abel Pallarés-Sanmartín, Eduardo Márquez, Agustin Valido-Morales, Ana Boldova Loscertales, Francisco Javier Callejas-Gonzalez and 5 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Exploring Clinical Control of COPD: Insights From a Portuguese Outpatient Population.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025
    Article
  3. Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study.International journal of chronic obstructive pulmonary disease · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Bernardino Alcazar-NavarreteAIG De Medicina. Hospital De Alta Resolución De Loja. Agencia Sanitaria Hospital De Poniente, Loja, Granada, Spain.ORCID 0000-0003-2356-9366
Antonia FusterServicio De Neumología. Hospital Universitario De Son Llatzer, Palma De Mallorca, Spain.
Patricia García SidroServicio De Neumología. Hospital De La Plana, Castellón, Spain.
Juan Luis García RiveroServicio De Neumología. Hospital De Laredo, Laredo, Spain.
Beatriz Abascal-BoladoServicio De Neumología. Hospital Universitario Marqués De Valdecilla, Santander, Spain.
Abel Pallarés-SanmartínServicio De Neumología. Hospital Universitario Alvaro Cunqueiro, Vigo, Spain.ORCID 0000-0001-9215-7299
Eduardo MárquezCIBERES. Instituto De Salud Carlos III, Madrid, Spain.
Agustin Valido-MoralesUGC De Neumología. HU Virgen Macarena, Sevilla, Spain.ORCID 0000-0002-8771-7463
Ana Boldova LoscertalesServicio De Neumología. Hospital Royo Villanova, Zaragoza, Spain.ORCID 0000-0001-9546-5369
Francisco Javier Callejas-GonzalezServicio De Neumología. Complejo Hospitalario Universitario De Albacete, Albacete, Spain.ORCID 0000-0001-8213-5424
Marta PalopServicio De Neumología. Hospital De Sagunto, Sagunto, Spain.
Juan Antonio RiescoCIBERES. Instituto De Salud Carlos III, Madrid, Spain.ORCID 0000-0002-7418-0759
Rafael GolpeServicio De Neumología. Hospital Universitario Lucus Augusti, Lugo, Spain.
Juan Jose Soler-CataluñaCIBERES. Instituto De Salud Carlos III, Madrid, Spain.
Marc MiravitllesCIBERES. Instituto De Salud Carlos III, Madrid, Spain.ORCID 0000-0002-9850-9520
Instituto de Salud Carlos III · ESAyuntamiento de Castellón de la Plana · ESComplejo Hospitalario Universitario de Albacete · ESHospital de Sagunto · ESHospital Royo Villanova · ESHospital Son Llatzer · ESHospital Universitario Lucus Augusti · ESHospital Universitario Virgen Macarena · ESMarqués de Valdecilla University Hospital · ESUniversity Hospital Complex Of Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The concept of clinical control has been proposed as an instrument for evaluating patients with COPD. However, the possible association between clinical control, reduced symptom severity and HRQoL has yet to be confirmed. Methods: This multicentre, prospective and observational study was carried out in 15 pulmonology clinics in Spain. The patients were followed up for six months, with a baseline visit (V0), followed by visits at three months (V1) and six months (V2). Clinical control was determined at V1, with the application of both clinical criteria and the COPD assessment test (CAT). All patients reported their symptoms by a validated symptom diary (E-RS) using a portable device, and their HRQoL was assessed using the EQ5D questionnaire. The relationship between clinical control and E-RS and HRQoL during follow-up was assessed with Results: A total of 126 patients were screened. After application of the inclusion/exclusion criteria, 93 were finally included (mean age 66 ± 8 years, 84.9% male), with a mean FEV Conclusion: Clinical control in patients with COPD, whether measured by CAT or by clinical criteria, is associated with a lower symptom load and a better HRQoL.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeFemaleHumansMaleProspective StudiesSpainSurveys and QuestionnairescontrolCOPDimpactquality of lifesymptoms

Identifiers

PMID33149566
PMCPMC7604255
OpenAlexW3097627473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.