Evidence map›Paper›PMID 33149503›Full record

ArticleJournal of pharmacy & bioallied sciences2020

Assessment of Efficacy of 5% Topical Amlexanox and 0.1% Topical Triamcinolone Acetonide in Management of Recurrent Aphthous Stomatitis.

Kumari Kavita, Rohit Singh, Revati Singh, Sudhir Gonuguntla, Alexander Maniangat Luke, Harshvardhan Shridhar Jois

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Kumari KavitaDepartment of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India.
Rohit SinghDepartment of Prosthodontics, Crown, Bridge and Implantology, Patna Dental College & Hospital, Patna, Bihar, India.
Revati SinghDepartment of Dentistry, Patna Medical College and Hospital (PMCH), Patna, Bihar, India.
Sudhir GonuguntlaDepartment of Oral and Maxillofacial Pathology, Malla Reddy Institute of Dental Sciences, Hyderabad, Telangana, India.
Alexander Maniangat LukeDepartment of Surgical Sciences, College of Dentistry, Ajman University, Ajman, UAE.
Harshvardhan Shridhar JoisDepartment of Oral Pathology, Army College of Dental Sciences, Secunderabad, Telangana, India.
Patna Medical College and Hospital · INAjman University · AEKamineni Institute of Dental Sciences · INNalanda Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to assess the efficacy of 5% topical amlexanox and 0.1% topical triamcinolone acetonide in recurrent aphthous stomatitis (RAS) management. MATERIALS AND

methodsSixty adult patients of RAS of both genders were divided into two groups with each group having 30 patients. In group I, 0.1% topical triamcinolone acetonide was prescribed. In group II, 5% topical amlexanox was prescribed. Patients were recalled regularly and size of ulcer, erythema, and pain score was recorded on days 1, 3, and 5.

resultsThe mean ulcer size (mm) on day 1 in group I was 4.3 and in group II it was 4.1, on day 3 it was 3.5 in group I and in group II it was 3.6, on day 5 in group I it was 1.3 and in group II it was 1.7. The result was not statistically significant (

conclusionAuthors found that above drugs were effective in reducing pain, size of ulcer, erythema, and improving healing in patients with recurrent aphthous stomatitis. There were better results with triamcinolone acetonide as comparison of amlexanox.

Indexed as

Amlexanoxrecurrent aphthous stomatitistriamcinolone acetonide

Identifiers

PMID33149503
PMCPMC7595536
OpenAlexW3081485102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.