ArticleJournal of pharmacy & bioallied sciences2020
Assessment of Salivary Flow Rate in Patients with Chronic Periodontitis.
Article in Journal of pharmacy & bioallied sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Prevalence of xerostomia and hyposalivation in older adults: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- The association between halitosis and periodontitis: a systematic review and meta-analysis.Clinical oral investigations · 2024Pooled it
- Taurine, Sirtuin-1 and TNF- α levels in different aged adults with periodontitis: a pilot study.BMC oral health · 2025Trial
- Oral status associated with xerostomia and oral health-related quality of life: an older population-based cross-sectional study in China.BMC geriatrics · 2026Article
- The Association of Periodontal Status, Salivary Flow Rate, Salivary Cortisol Levels, and Cytokine Levels with Cognitive Status in Elderly Subjects.Geriatrics (Basel, Switzerland) · 2025Article
- Impact of perinatal HIV exposure and infection on salivary properties among Nigerian children.BMC oral health · 2024Article
- Investigation of volatile sulfur compound level and halitosis in patients with gingivitis and periodontitis.Scientific reports · 2023Article
- Article
- Associations between salivary cytokines and oral health, age, and sex in healthy children.Scientific reports · 2022Article
- Novel impacts of saliva with regard to oral health.The Journal of prosthetic dentistry · 2022Review
- Association of general health and lifestyle factors with the salivary microbiota - Lessons learned from the ADDITION-PRO cohort.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic periodontitis (CP) is an infectious disease, primarily affecting the attachment apparatus of the dentition, and is categorized into mild, moderate, and severe periodontitis on the basis of its severity. It is a well-established and proven fact that an adequate level of saliva is essential for maintaining the integrity of oral tissues including the periodontium. Although various factors, such as stimulation, circadian rhythm, diet, age, and drugs, can affect the salivary flow rate, many recent studies have provided evidence that it can be altered by pathological inflammatory conditions such as periodontal diseases. Therefore, this study has been undertaken to assess the unstimulated and stimulated salivary flow rate in the different clinical stages of chronic periodontitis. MATERIALS AND
methodsThis study comprised 60 study participants, who were divided into four groups depending on clinical attachment level (CAL). In all, both unstimulated and stimulated saliva were collected, and the flow rate was expressed in milliliter per minute.
resultsStatistical analysis was accomplished with Statistical Package for the Social Sciences (SPSS) software. One-way analysis of variance (ANOVA) was used to analyze differences in salivary flow rate among the groups. Statistical significance was set at
conclusionThe study identified a significant decrease in both unstimulated and stimulated salivary flow rate with the severity of progression of chronic periodontitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.