Evidence map›Paper›PMID 33149256›Full record

ArticleScientific reports2020

Efficacy of S-PRG filler containing varnishes on enamel demineralization prevention.

Manuela da Silva Spinola, Sabrina Elise Moecke, Natália Rivoli Rossi, Toshiyuki Nakatsuka, Alessandra Bühler Borges, Carlos Rocha Gomes Torres

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Biological Effects on S-PRG: An Integrative Review.Journal of functional biomaterials · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
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  12. Article
  13. Effects of SrBiological trace element research · 2023
    Article
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  15. Article
  16. Article
  17. Article
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  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Manuela da Silva SpinolaDepartment of Restorative Dentistry, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Sabrina Elise MoeckeDepartment of Restorative Dentistry, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Natália Rivoli RossiDepartment of Dental Materials and Prosthodontics, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Toshiyuki NakatsukaDepartment of Research and Development, Shofu Inc., 11 Kamitakamatsu-cho, Fukuine, Higashiyama-ku, Kyoto, 605-0983, Japan.
Alessandra Bühler BorgesDepartment of Restorative Dentistry, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
Carlos Rocha Gomes TorresDepartment of Restorative Dentistry, São Paulo State University - UNESP, Institute of Science and Technology, Av. Eng. Francisco Jose Longo, 777, São José dos Campos, SP, 12245-000, Brazil. carlos.rg.torres@unesp.br.
Universidade Estadual Paulista (Unesp) · BRShofu (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the efficacy of S-PRG vanishes on preventing enamel demineralization. Bovine enamel specimens were obtained, polished and the baseline Knoop microhardness was evaluated. Specimens were stratified into six groups (n = 15), according to the varnish applied: S10-experimental varnish containing 10% of S-PRG fillers, S20-20% of S-PRG fillers, S30-30% of S-PRG fillers; S40-40% of S-PRG fillers; PC (positive control)-5% of NaF; NC (negative control)-no treatment was performed. Half of enamel surfaces were protected to work as a control and varnishes were applied over the unprotected area. A demineralizing pH-cycling was performed, and surface and cross-sectional microhardness were measured. The percentage of microhardness of the treated area was calculated comparing with the untreated area. Statistical analysis was performed by one-way ANOVA and Tukey's test (p = 5%). All experimental S-PRG varnishes protected against demineralization in relation to no treatment, but S40 was the most effective on the surface. For all depths, S30 and S40 were superior in enamel demineralization prevention than other S-PRG filler concentrations and 5% NaF. It was concluded that S-RPG filler containing varnishes were effective to prevent enamel demineralization. The higher concentrated products were more effective than 5% sodium fluoride on surface demineralization prevention.

Identifiers

PMID33149256
PMCPMC7642416
OpenAlexW3097182843

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.