Evidence map›Paper›PMID 33149185›Full record

ArticleScientific reports2020

Genome wide association study of passive immunity and disease traits in beef-suckler and dairy calves on Irish farms.

Dayle Johnston, Robert Mukiibi, Sinéad M Waters, Mark McGee, Carla Surlis, Jennifer C McClure, Matthew C McClure, Cynthia G Todd, Bernadette Earley

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Dayle JohnstonAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland.
Robert MukiibiThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, EH25 9RG, UK.
Sinéad M WatersAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland.
Mark McGeeAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland.
Carla SurlisAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland.
Jennifer C McClureIrish Cattle Breeding Federation, Cork, P72 X050, Ireland.
Matthew C McClureIrish Cattle Breeding Federation, Cork, P72 X050, Ireland.
Cynthia G ToddAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland.
Bernadette EarleyAnimal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, C15 PW93, Co. Meath, Ireland. bernadette.earley@teagasc.ie.
Teagasc - The Irish Agriculture and Food Development Authority · IEUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calves with lower concentrations of immunoglobulin G (IgG) in their blood, have a greater risk of developing diseases. There is a lack of knowledge on genetic markers known to be associated with immunological variability or disease resistance. Therefore, the objective of this study was to identify SNP markers associated with passive immunity measures (serum IgG, serum protein, albumin, globulin and total protein concentrations, total solids Brix percentage, zinc sulphate turbidity units) and disease (pneumonia, diarrhoea, crude illness) traits in Irish commercial beef-suckler and dairy calves through genome wide association studies (GWAS). Genotyping was performed on DNA samples from beef-suckler (n = 698) and dairy (n = 1178) calves, using the IDBv3 chip. Heritability of passive immunity associated traits (range 0.02-0.22) and the disease traits (range 0.03-0.20) were low-to-moderate. Twenty-five and fifteen SNPs approached genome wide significance (P < 5 × 10

Indexed as

Polymorphism, Single NucleotideAnimalsAnimals, SucklingCattleDisease ResistanceFemaleGenome-Wide Association StudyGenotyping TechniquesImmunity, Maternally-AcquiredImmunoglobulin GIrelandQuantitative Trait, HeritableImmunoglobulin G

Identifiers

PMID33149185
PMCPMC7643155
OpenAlexW3095530914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.