ArticleNature communications2020
Metabolite signatures of diverse Camellia sinensis tea populations.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 78 papers, 1 of them a synthesis that pooled it.
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Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models.Molecules (Basel, Switzerland) · 2021Pooled it
- Non-volatile metabolomic differentiation of geographical origin and quality grade in pre-Qingming Xihu Longjing green tea using in-source fragment ion-assisted annotation.Food chemistry: X · 2026Article
- Integrated metabolomic and transcriptomic analysis of Camellia sinensis var. pubilimba 'Rucheng Baimaocha' reveals distinct flavonoid and strictinin biosynthesis.BMC plant biology · 2026Article
- Genetic diversity and population structure of wild and cultivated Camellia tetracocca Chang assessed by ILP markers: insights for conservation of an endangered tea species.BMC plant biology · 2026Article
- Genome characterization of a novel betaflexivirus from the wild tea plant Camellia taliensis.Archives of virology · 2026Article
- Chromosome level genome assembly of Camellia sinensis 'Yuwan Xiaoye'.Scientific data · 2026Article
- Systematic Metabolic Engineering and Model-Guided Optimization for High-Level Production of L-Theanine from Xylose in Escherichia coli.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Effects of different intercropping patterns on tea rhizosphere environment and leaf quality.Frontiers in plant science · 2026Article
- Article
- Integrative analysis of morphological traits and targeted flavonoid profiles reveals chemotaxonomic signatures inFrontiers in plant science · 2026Article
- Integrated single-nucleus transcriptomic and metabolomic insights into bud-to-leaf development and metabolite synthesis in tea plant.Horticulture research · 2026Article
- Pangenome analyses of tea plants reveal structural variations driving gene expression alterations and agronomic trait diversification.Nature communications · 2025Article
- Rhizosphere microbial diversity and functional roles in tea cultivars: insights from high-throughput sequencing and functional isolates.Plant signaling & behavior · 2025Article
- Integrated metabolomic and transcriptomic analyses reveal cultivar-specific molecular responses of tea plants growing in Northern China.BMC plant biology · 2025Article
- Differential Metabolic Analysis of Rhizomes in Shancigu Based on Widely Targeted Metabolomics.Metabolites · 2025Article
- Non-Targeted Metabolomics and Network Pharmacology Reveal Bioactive Metabolites and the Medicinal Potential of Three Ornamental Camellia Flowers.Plants (Basel, Switzerland) · 2025Article
- Profiling Environmental Variations in Condensed Tannins and Other Metabolites of Birdsfoot Trefoil (Plants (Basel, Switzerland) · 2025Article
- Effect of tea manufacturing processes and cultivars on tea infusion color.Scientific reports · 2025Article
- The Scarlet Alchemy of Survival: Integrated Transcriptomic and Metabolomic Analysis of Leaf Coloration in EndangeredPlants (Basel, Switzerland) · 2025Article
- Metabolomics and transcriptomics reveal the quality formation mechanism during the processing of black tea.NPJ science of food · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tea plant (Camellia sinensis) presents an excellent system to study evolution and diversification of the numerous classes, types and variable contents of specialized metabolites. Here, we investigate the relationship among C. sinensis phylogenetic groups and specialized metabolites using transcriptomic and metabolomic data on the fresh leaves collected from 136 representative tea accessions in China. We obtain 925,854 high-quality single-nucleotide polymorphisms (SNPs) enabling the refined grouping of the sampled tea accessions into five major clades. Untargeted metabolomic analyses detect 129 and 199 annotated metabolites that are differentially accumulated in different tea groups in positive and negative ionization modes, respectively. Each phylogenetic group contains signature metabolites. In particular, CSA tea accessions are featured with high accumulation of diverse classes of flavonoid compounds, such as flavanols, flavonol mono-/di-glycosides, proanthocyanidin dimers, and phenolic acids. Our results provide insights into the genetic and metabolite diversity and are useful for accelerated tea plant breeding.
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