Evidence map›Paper›PMID 33148933›Full record

ReviewJournal of clinical and experimental hematopathology : JCEH2020

Pathogenesis of chronic lymphocytic leukemia and the development of novel therapeutic strategies.

Yoshikane Kikushige

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hematopathology : JCEH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07154823 (A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07154823 recruitingnot on this mapstarted 2026, after this paper: background citation

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

Typeobservational_patient_registrySponsorTempus AIRan2026 to 2035Enrolled550ConditionsAcute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)ArmsNone - Observational Study
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Polyfunctional CD8Molecular oncology · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. PI3k Inhibitors in NHL and CLL: An Unfulfilled Promise.Blood and lymphatic cancer : targets and therapy · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yoshikane KikushigeDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, Japan.
Kyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries and is characterized by the clonal expansion of mature CD5

Indexed as

CarcinogenesisLeukemia, Lymphocytic, Chronic, B-CellMolecular Targeted TherapyMutationAdultHumansBCR signalingchronic lymphocytic leukemiamultistep leukemogenesisnovel drugs

Identifiers

PMID33148933
PMCPMC7810248
OpenAlexW3096602912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.