Evidence map›Paper›PMID 33148877›Full record

ArticleActa crystallographica. Section C, Structural chemistry2020

Crystal structures of salts of bedaquiline.

Mercy Okezue, Daniel Smith, Matthias Zeller, Stephen R Byrn, Pamela Smith, Susan Bogandowich-Knipp, Dale K Purcell, Kari L Clase

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Comparison of pharmacokinetics and bioavailability of bedaquiline fumarate, benzoate and maleate in dogs.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  3. Article
  4. Maleate salts of bedaquiline.Acta crystallographica. Section E, Crystallographic communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mercy OkezuePurdue University, Industrial and Physical Pharmacy, 575 Stadium Mall, West Lafayette, IN 47907, USA.
Daniel SmithPurdue University, Industrial and Physical Pharmacy, 575 Stadium Mall, West Lafayette, IN 47907, USA.
Matthias ZellerPurdue University, Chemistry, 560 Oval Drive, West Lafayette, IN 47907-2084, USA.ORCID 0000-0002-3305-852X
Stephen R ByrnPurdue University, Industrial and Physical Pharmacy, 575 Stadium Mall, West Lafayette, IN 47907, USA.
Pamela SmithLeading with Smart Science, LLC, 5315 Shootingstar Lane, West Lafayette, IN 47906, USA.
Susan Bogandowich-KnippRavine Pharmaceuticals, LLC, 3425 DuBois Street, West Lafayette, IN 47906, USA.
Dale K PurcellChemical Microscopy, LLC, 1281 Win Hentschel Boulevard, West Lafayette, IN 47906, USA.
Kari L ClasePurdue University, Industrial and Physical Pharmacy, 575 Stadium Mall, West Lafayette, IN 47907, USA.ORCID 0000-0003-2749-6440
Purdue University West Lafayette · USState Street (United States) · US

Funding

National Science Foundation, Directorate for Mathematical and Physical Sciences 1625543
6 · The paper itself

Abstract

Bedaquiline [systematic name: 1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol, C

Indexed as

bedaquilinebedaqulinium saltcrystal structuredrug-resistant tuberculosis

Identifiers

PMID33148877
PMCPMC7642769
OpenAlexW3093967985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.