ArticleJournal of virology2021
Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level.
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Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 54 citations in OpenAlex.
- Herpes simplex virus pUL56 abolishes neuronal activity by removing voltage-gated ion channels from the plasma membrane.Science advances · 2026Article
- Herpes simplex virus type 1 interferes with signal transducer and activator of transcription 3 expression in infected mature dendritic cells.The Journal of general virology · 2026Article
- Nuclear speckles are regulatory hubs for viral and host mRNA expression during HSV-1 infection.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Infection Dynamics and Host Responses to Two IPNV Isolates in Liver of Atlantic Salmon (Pathogens (Basel, Switzerland) · 2025Article
- DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts.The Journal of experimental medicine · 2025Article
- Article
- Herpes simplex virus-1 infection alters microtubule-associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease.Brain pathology (Zurich, Switzerland) · 2025Article
- DUX4 at 25: how it emerged from "junk DNA" to become the cause of facioscapulohumeral muscular dystrophy.Skeletal muscle · 2025Review
- Structural host-virus interactome profiling of intact infected cells.Nature communications · 2025Article
- Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking.Nature communications · 2025Article
- HSV-1 infection induces a downstream shift of the +1 nucleosome.Journal of virology · 2025Article
- Temporal transcriptional profiling of host cells infected by a veterinary alphaherpesvirus using nanopore sequencing.Scientific reports · 2025Article
- Herpesviruses mimic zygotic genome activation to promote viral replication.Nature communications · 2025Article
- HSV-1 ICP22 condensates impair host transcription by depleting promoter RNAPII Ser-2P occupation.Frontiers in microbiology · 2025Article
- Rapid glycoprotein evolution enables variant interactions in herpes simplex virus type 1.Virus evolution · 2025Article
- Pseudorabies Virus UL41 Hijacks IFN Response via JAK/STAT Pathway While Cellular TRIM21 Blocks it Through K48 Ubiquitination.Transboundary and emerging diseases · 2025Article
- HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.Cell reports · 2024Article
- Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection.iScience · 2024Article
- Herpesviruses mimic zygotic genome activation to promote viral replication.Research square · 2023Article
- Alphaherpesvirus-mediated remodeling of the cellular transcriptome results in depletion of m6A-containing transcripts.iScience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 2 countries.
Caroline C Friedel *Institute of Informatics, Ludwig-Maximilians-Universität München, Munich, Germany caroline.friedel@bio.ifi.lmu.de lars.doelken@uni-wuerzburg.de.ORCID 0000-0003-3569-4877
Adam W Whisnant *Institute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Lara Djakovic *Institute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Andrzej J RutkowskiDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Marie-Sophie FriedlInstitute of Informatics, Ludwig-Maximilians-Universität München, Munich, Germany.
Michael KlugeInstitute of Informatics, Ludwig-Maximilians-Universität München, Munich, Germany.
James C WilliamsonDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Somesh SaiMax Delbrück Center for Molecular Medicine/Berlin Institute of Health, Berlin, Germany.
Ramon Oliveira VidalMax Delbrück Center for Molecular Medicine/Berlin Institute of Health, Berlin, Germany.
Sascha SauerMax Delbrück Center for Molecular Medicine/Berlin Institute of Health, Berlin, Germany.
Thomas HennigInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Arnhild GrotheyInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Andrea MilićInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Bhupesh K PrustyInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Paul J LehnerDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Nicholas J MathesonDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Florian ErhardInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Lars DölkenInstitute for Virology and Immunobiology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany caroline.friedel@bio.ifi.lmu.de lars.doelken@uni-wuerzburg.de.
University of Würzburg · DEUniversity of Cambridge · GBLudwig-Maximilians-Universität München · DEMax Delbrück Center · DE
Funding
Cancer Research UK CSF G1002523Cancer Research UK MR/P008801/1Medical Research Council G1002523Medical Research Council MR/P008801/1Wellcome TrustWellcome Trust PRF 210688/Z/18/Z
Abstract
Herpes simplex virus 1 (HSV-1) induces a profound host shutoff during lytic infection. The virion host shutoff (
Indexed as
Gene Expression Regulation, ViralVirus ReplicationFibroblastsHerpes SimplexHerpesvirus 1, HumanHumansProtein BiosynthesisProteomeRibonucleasesRNA, ViralTranscriptomeViral ProteinsProteomeRibonucleasesRNA, ViralViral Proteinsvirion host shutoff protein, Simplexvirus4sU-seqchromatin-associated RNAherpes simplex virus 1proteomicsRNA degradationRNA-seqtranscriptional regulationvirion host shutoff protein
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.