Evidence map›Paper›PMID 33148675›Full record

Observational studyClinical cancer research : an official journal of the American Association for Cancer Research2021

Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model.

Maren M Sjaastad Andreassen, Ana E Rodríguez-Soto, Christopher C Conlin, Igor Vidić, Tyler M Seibert, Anne M Wallace, Somaye Zare, Joshua Kuperman, Boya Abudu, Grace S Ahn and 8 more

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Clinical cancer research : an official journal of the American Association for Cancer Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Longitudinal registration of TMagnetic resonance imaging · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maren M Sjaastad Andreassen *Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-2581-7135
Ana E Rodríguez-Soto *Department of Radiology, University of California San Diego, La Jolla, California.
Christopher C ConlinDepartment of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0003-4509-8702
Igor VidićDepartment of Physics, Norwegian University of Science and Technology, Trondheim, Norway.
Tyler M SeibertDepartment of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0002-4089-7399
Anne M WallaceDepartment of Surgery, University of California San Diego, La Jolla, California.
Somaye ZareDepartment of Pathology, University of California San Diego, La Jolla, California.ORCID 0000-0003-4910-8795
Joshua KupermanDepartment of Radiology, University of California San Diego, La Jolla, California.
Boya AbuduSchool of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0002-7552-6141
Grace S AhnSchool of Medicine, University of California San Diego, La Jolla, California.
Michael HahnDepartment of Radiology, University of California San Diego, La Jolla, California.
Neil P JeromeDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-9556-5930
Agnes ØstlieDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Tone F BathenDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-8582-6965
Haydee Ojeda-FournierDepartment of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0003-3773-0050
Pål Erik GoaDepartment of Physics, Norwegian University of Science and Technology, Trondheim, Norway.
Rebecca Rakow-Penner *Department of Radiology, University of California San Diego, La Jolla, California. rrakowpenner@health.ucsd.edu.
Anders M Dale *Department of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0002-6126-2966

Funding

Improving assessment of prostate cancer bone metastases using advanced diffusion imagingK08EB026503 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEIBERT, TYLER MICHAEL · 2019 to 2022
$805k
NCI NIH HHS L30 CA231417NIBIB NIH HHS K08 EB026503
6 · The paper itself

Abstract

purposeDiffusion-weighted MRI (DW-MRI) is a contrast-free modality that has demonstrated ability to discriminate between predefined benign and malignant breast lesions. However, how well DW-MRI discriminates cancer from all other breast tissue voxels in a clinical setting is unknown. Here we explore the voxelwise ability to distinguish cancer from healthy breast tissue using signal contributions from the newly developed three-component multi-b-value DW-MRI model. EXPERIMENTAL

designPatients with pathology-proven breast cancer from two datasets (

resultsMean FPR

conclusionsThe

Indexed as

Image Processing, Computer-AssistedAdultAgedAged, 80 and overBreastBreast NeoplasmsDatasets as TopicDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFeasibility StudiesFemaleHumansMiddle AgedROC CurveYoung Adult

Identifiers

PMID33148675
PMCPMC8174004

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.