Evidence map›Paper›PMID 33148647›Full record

ArticleScience advances2020

A single-cell analysis of the molecular lineage of chordate embryogenesis.

Tengjiao Zhang, Yichi Xu, Kaoru Imai, Teng Fei, Guilin Wang, Bo Dong, Tianwei Yu, Yutaka Satou, Weiyang Shi, Zhirong Bao

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. The specious art of single-cell genomics.PLoS computational biology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Quantitative Dissection of the ProximalFrontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Tengjiao ZhangInstitute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200123, China.ORCID 0000-0001-7815-2504
Yichi XuDevelopmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA.ORCID 0000-0002-8163-3920
Kaoru ImaiDepartment of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.ORCID 0000-0001-9113-6074
Teng FeiDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0001-7888-1715
Guilin WangMinistry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-6749-5250
Bo DongMinistry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-1616-5363
Tianwei YuSchool of Data Science, The Chinese University of Hong Kong-Shenzhen, Shenzhen, Guangdong 518172, China.
Yutaka SatouDepartment of Zoology, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.ORCID 0000-0001-5193-0708
Weiyang ShiMinistry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China. baoz@mskcc.org wshi@ouc.edu.cn.ORCID 0000-0001-7678-2131
Zhirong BaoDevelopmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA. baoz@mskcc.org wshi@ouc.edu.cn.ORCID 0000-0002-2201-2745
Ocean University of China · CNKettering University · USChinese University of Hong Kong, Shenzhen · CNEmory University · USKyoto University · JPShanghai East Hospital · CNThe University of Osaka · JP

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
The Ubiquitin-Proteasome System in Metazoan EmbryogenesisR01GM097576 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAO, ZHIRONG · 2011 to 2020
$3.3M
Bayesian Network Biomarker Selection in Metabolomics DataR01GM124061 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KANG, JIAN · 2017 to 2020
$1.4M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM097576NIGMS NIH HHS R01 GM124061
6 · The paper itself

Abstract

Progressive unfolding of gene expression cascades underlies diverse embryonic lineage development. Here, we report a single-cell RNA sequencing analysis of the complete and invariant embryonic cell lineage of the tunicate

Indexed as

Ciona intestinalisAnimalsCell LineageFibroblast Growth FactorsGene Expression Regulation, DevelopmentalMiceNotochordSingle-Cell AnalysisFibroblast Growth Factors

Identifiers

PMID33148647
PMCPMC7673699
OpenAlexW3095240268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.