Evidence map›Paper›PMID 33148623›Full record

ArticleScience translational medicine2020

Multimodal imaging of bacterial-host interface in mice and piglets with

Peter Panizzi, Marvin Krohn-Grimberghe, Edmund Keliher, Yu-Xiang Ye, Jana Grune, Vanessa Frodermann, Yuan Sun, Charlotte G Muse, Kaitlyn Bushey, Yoshiko Iwamoto and 24 more

Open access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Neutrophils Protect AgainstArteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  6. Article
  7. Arteriosclerosis, thrombosis, and vascular biology · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 10 institutions in 4 countries.

Peter PanizziDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-0141-8807
Marvin Krohn-GrimbergheCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-5753-7330
Edmund KeliherCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-6607-0760
Yu-Xiang YeCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.
Jana GruneCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.
Vanessa FrodermannCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-5566-6692
Yuan SunCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-3514-1992
Charlotte G MuseDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-4412-0250
Kaitlyn BusheyGreen Mountain Antibodies, Burlington, VT 05401, USA.
Yoshiko IwamotoCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.
Mandy M T van LeentBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9747-1022
Anu MeerwaldtBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-5662-6828
Yohana C TonerBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-5309-6366
Jazz MunitzBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9173-2666
Alexander MaierBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Georgios SoultanidisBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-9620-1728
Claudia CalcagnoBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Carlos Pérez-MedinaBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-6011-0629
Giuseppe CarlucciBernard and Irene Schwarz Center for Biomedical Imaging, New York University, New York, NY 10016, USA.
Kay P RiddellDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
Sharron BarneyDepartment of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
Glenn HorneDepartment of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
Brian AndersonSwine Research and Education Center, Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-1334-8714
Ashoka Maddur-AppajaiahDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
Ingrid M VerhammeDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
Paul E BockDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
Gregory R WojtkiewiczCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-3148-8411
Gabriel CourtiesCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-0003-7407
Filip K SwirskiCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.
William R ChurchGreen Mountain Antibodies, Burlington, VT 05401, USA.
Paul H WalzDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
D Michael TillsonDepartment of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
Willem J M MulderBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-8665-3878
Matthias NahrendorfCenter for Systems Biology and Department of Radiology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA. mnahrendorf@mgh.harvard.edu.ORCID 0000-0002-4021-1887
Center for Systems Biology · USAuburn University · USIcahn School of Medicine at Mount Sinai · USVanderbilt University Medical Center · USResearch & Diagnostic Antibodies (United States) · USCentro Nacional de Epidemiología · ESEindhoven University of Technology · NLHarvard University · USNew York University · USUniversity of Freiburg · DE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
Imaging organ system interfaces in ischemic heart diseaseR35HL139598 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS · 2018 to 2024
$6.9M
Atherosclerosis in cocaine addiction: imaging risk with PET/MRR01DA049547 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nelly Alia-Klein, Zahi A. Fayad · 2022 to 2026
$3.9M
PET nanoreporter image-guided breast cancer therapyR01CA220234 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A., PÉREZ-MEDINA, CARLOS · 2018 to 2022
$3.6M
TRAF6 Nanoimmunotherapy to resolve plaque inflammationR01HL144072 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2018 to 2021
$3.3M
Mechanism of Staphylocoagulase-activated Blood ClottingR37HL071544 · NHLBI · VANDERBILT UNIVERSITY · PI BOCK, PAUL E · 2004 to 2012
$2.9M
Quantitative nanoparticle imaging of macrophagesR01HL131495 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS, WEISSLEDER, MD, PHD, RALPH · 2017 to 2020
$2.7M
Mechanism of Staphylocoagulase-activated Blood ClottingR01HL071544 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BOCK, PAUL E, VERHAMME, INGRID M · 2003 to 2016
$1.8M
Pathogen specific imaging of endocarditisR01HL114477 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS, PANIZZI, PETER ROLF · 2013 to 2016
$1.7M
Mechanisms of Glycosaminoglycan-Catalyzed Protease Inactivation by SerpinsR01HL130018 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VERHAMME, INGRID M · 2016 to 2019
$1.6M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA220234NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL071544NHLBI NIH HHS R01 HL114477NHLBI NIH HHS R01 HL130018NHLBI NIH HHS R01 HL131495NHLBI NIH HHS R01 HL144072NHLBI NIH HHS R35 HL139598NHLBI NIH HHS R37 HL071544NIBIB NIH HHS P41 EB017183NIDA NIH HHS R01 DA049547
6 · The paper itself

Abstract

Acute bacterial endocarditis is a rapid, difficult to manage, and frequently lethal disease. Potent antibiotics often cannot efficiently kill

Indexed as

Endocarditis, BacterialStaphylococcal InfectionsAnimalsCoagulaseMiceMultimodal ImagingStaphylococcus aureusSwineCoagulase

Identifiers

PMID33148623
PMCPMC7818516
OpenAlexW3096355723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.