Evidence map›Paper›PMID 33148598›Full record

ArticleBMJ case reports2020

Amiodarone-induced neuromyopathy in a geriatric patient.

Michael Mark Stanton, Leyla Samii, Gentson Leung, Paula Pearce

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Uncommon neuromyopathy toxicity induced by amiodarone therapy: case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael Mark StantonDivision of Geriatrics, Department of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada michael.stanton@albertahealthservices.ca.
Leyla SamiiDivision of Geriatrics, Department of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Gentson LeungDivision of Physical Medicine and Rehabilitation, Department of Clinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Paula PearceDivision of Geriatrics, Department of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amiodarone is an antiarrhythmic medication with many side effects. Neuromyopathy is a rare adverse effect. We present an 87-year-old woman with bilateral leg pain and weakness in the context of amiodarone. She was admitted to the Acute Geriatric Unit in Calgary, Alberta, Canada. On examination, hip flexor and extensor strength were 2/5 bilaterally while knee flexor and extensor strength were 4/5 and 3/5, respectively. Creatine kinase and C-reactive protein levels were normal. MRI of the lumbar spine showed mild central canal stenosis. Electromyography and nerve conduction testing showed a severe axonal length-dependent polyneuropathy of the left lower extremity. There was evidence of myopathic changes to the left iliopsoas muscle. Overall, a neuromyopathic process affecting the lower extremities was supported. After discontinuation of amiodarone, mobility and function significantly improved. Although a rare complication of amiodarone, neuromyopathy should be considered in patients with compatible symptomatology.

Indexed as

Aged, 80 and overAmiodaroneAnti-Arrhythmia AgentsAtrial FibrillationElectromyographyFemaleHumansLower ExtremityMuscle, SkeletalNeuromuscular DiseasesTomography, X-Ray ComputedAmiodaroneAnti-Arrhythmia Agentsarrhythmiasgeriatric medicinemuscle diseaseunwanted effects / adverse reactions

Identifiers

PMID33148598
PMCPMC7643464
OpenAlexW3096871107

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.