Evidence map›Paper›PMID 33148560›Full record

ArticleBMJ case reports2020

Bilateral, vertical supranuclear gaze palsy following unilateral midbrain infarct.

Yunfei Yang, Umair Qidwai, Benjamin J L Burton, Carlo Canepa

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Locked-in syndrome revisited.Therapeutic advances in neurological disorders · 2023
    Review
  5. Neurological implications of cardiac compromise in COVID-19.American journal of cardiovascular disease · 2023
    Review
  6. Post-COVID-19 fatal Aspergillus endocarditis: A case report.Journal of clinical laboratory analysis · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yunfei YangAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK yunfei.yang@nhs.net.ORCID http://orcid.org/0000-0002-7130-9801
Umair QidwaiJames Paget University Hospital, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.
Benjamin J L BurtonJames Paget University Hospital, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.
Carlo CanepaJames Paget University Hospital, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.
James Paget University Hospitals NHS Foundation Trust · GBCambridge University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 60-year-old man recently admitted for bipedal oedema, endocarditis and a persistently positive COVID-19 swab with a history of anticoagulation on rivaroxaban for atrial fibrillation, transitional cell carcinoma, cerebral amyloid angiopathy, diabetes and hypertension presented with sudden onset diplopia and vertical gaze palsy. Vestibulo-ocular reflex was preserved. Simultaneously, he developed a scotoma and sudden visual loss, and was found to have a right branch retinal artery occlusion. MRI head demonstrated a unilateral midbrain infarct. This case demonstrates a rare unilateral cause of bilateral supranuclear palsy which spares the posterior commisure. The case also raises a question about the contribution of COVID-19 to the procoagulant status of the patient which already includes atrial fibrillation and endocarditis, and presents a complex treatment dilemma regarding anticoagulation.

Indexed as

Atrial FibrillationBlindnessBrain Stem InfarctionsCoronavirus InfectionsDiplopiaEndocarditis, BacterialOphthalmoplegiaPandemicsPneumonia, ViralRetinal Artery OcclusionAspirinBetacoronavirusCOVID-19Factor Xa InhibitorsHumansMagnetic Resonance ImagingapixabanAspirinFactor Xa InhibitorsPlatelet Aggregation InhibitorsPyrazolesPyridonescontraindications and precautionsneuroopthalmologystrokeTB and other respiratory infectionsvisual pathway

Identifiers

PMID33148560
PMCPMC7643481
OpenAlexW3096427671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.