Evidence map›Paper›PMID 33148295›Full record

ReviewJournal of ovarian research2020

Therapeutic role of curcumin and its novel formulations in gynecological cancers.

Mohammad Hossein Pourhanifeh, Maryam Darvish, Javad Tabatabaeian, Mahboobeh Rabbani Fard, Reza Mottaghi, Mohammad Javad Azadchehr, Moghaddaseh Jahanshahi, Amirhossein Sahebkar, Hamed Mirzaei

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of ovarian research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  8. Article
  9. Article
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  13. Article
  14. Review
  15. Copper in Gynecological Diseases.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines.Anti-cancer agents in medicinal chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad Hossein PourhanifehHalal Research Center of IRI, FDA, Tehran, Iran.
Maryam DarvishDepartment of Medical Biotechnology, Faculty of Medicine, Arak University of Medical Science, Arak, Iran. maryam_darvish@yahoo.com.
Javad TabatabaeianFaculty of Member, Ardestan Branch, Islamic Azad University, Ardestan, Iran.
Mahboobeh Rabbani FardFaculty of Member, Ardestan Branch, Islamic Azad University, Ardestan, Iran.
Reza MottaghiDepartment of Oral and Maxillofacial Surgery, Kashan University of Medical Sciences, Kashan, Iran.
Mohammad Javad AzadchehrTrauma Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Moghaddaseh JahanshahiClinical Research Development Center (CRDC), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Amirhossein SahebkarNeurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hamed MirzaeiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. h.mirzaei2002@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gynecological cancers are among the leading causes of cancer-associated mortality worldwide. While the number of cases are rising, current therapeutic approaches are not efficient enough. There are considerable side-effects as well as treatment resistant types. In addition, which all make the treatment complicated for afflicted cases. Therefore, in order to improve efficacy of the treatment process and patients' quality of life, searching for novel adjuvant treatments is highly warranted. Curcumin, a promising natural compound, is endowed with numerous therapeutic potentials including significant anticancer effects. Recently, various investigations have demonstrated the anticancer effects of curcumin and its novel analogues on gynecological cancers. Moreover, novel formulations of curcumin have resulted in further propitious effects. This review discusses these studies and highlights the possible underlying mechanisms of the observed effects.

Indexed as

CurcuminFemaleGenital Neoplasms, FemaleHumansCurcuminCervical cancerCurcuminCurcumin derivativesEndometrial cancerNanocurcuminNatural compoundOvarian cancer

Identifiers

PMID33148295
PMCPMC7643381

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.