Evidence map›Paper›PMID 33148221›Full record

ArticleBMC nephrology2020

Prevalence and factors associated with pulmonary arterial hypertension on maintenance hemodialysis patients in Kinshasa, Democratic Republic of Congo: a cross-sectional study.

Yannick Mompango Engole, François Bompeka Lepira, Yannick Mayamba Nlandu, Yves Simbi Lubenga, Augustin Luzayadio Longo, Aliocha Nkodila, Jean-Robert Rissassy Makulo, Vieux Momeme Mokoli, Justine Busanga Bukabau, Marie-France Ingole Mboliasa and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Risk Factors of Pulmonary Hypertension in Patients on Hemodialysis: A Single Center Study.International journal of nephrology and renovascular disease · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Yannick Mompango EngoleNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo. yannickengole@yahoo.fr.ORCID 0000-0002-8795-5525
François Bompeka LepiraNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Yannick Mayamba NlanduNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Yves Simbi LubengaCardiology Unit, University Hospital of Kinshasa, BP: 123, Kinshasa, XI, Democratic Republic of the Congo.
Augustin Luzayadio LongoNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Aliocha NkodilaNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean-Robert Rissassy MakuloNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Vieux Momeme MokoliNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Justine Busanga BukabauNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Marie-France Ingole MboliasaNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Evariste Mukendi KadimaNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Cedric Kabemba IlungaNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Tresor Swambulu MvunziCardiology Unit, University Hospital of Kinshasa, BP: 123, Kinshasa, XI, Democratic Republic of the Congo.
Nazaire Mangani NsekaNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Ernest Kiswaya SumailiNephrology Unit, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo.
University of Kinshasa · CDKinshasa General Hospital · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough cardiovascular diseases in particular Pulmonary Arterial Hypertension (PAH) is associated with, high morbid-mortality in chronic hemodialysis, but its magnitude remains paradoxically unknown in sub-Saharan Africa. The aim of this study was to evaluate the prevalence of PAH and associated factors in chronic hemodialysis in Sub-Saharan African population.

methodIn a cross-sectional study, patients treated with HD for at least 6 months in 4 hemodialysis centers were examined. PAH was defined as estimated systolic pulmonary arterial pressure (sPAP) ≥ 35 mmHg using transthoracic Doppler echocardiography performed 24 h after the HD session.

resultsEighty-five HD patients were included; their average age was 52.6 ± 15.9 years. Fifty-seven patients (67.1%) were male. Mean duration of HD was 13.3 ± 11 months. With reference to vascular access, 12 (14.1%), 29 (34.1%) and 44 (51.8%) patients had AVF, tunneled cuff and temporary catheter, respectively. The underlying cause of ESRD was diabetes in 30 patients (35.3%). The prevalence of PAH was 29.4%. Patients with PAH had more hyponatremia (11 (44%) vs 10 (16.7%), p = 0.010). In multivariate analysis, unsecured healthcare funding (aOR 4, 95% CI [1.18-6.018]), arrhythmia (aOR 3, 95% CI [1.29-7.34]), vascular access change (aOR 4, 95% CI [1.18-7.51]) and diastolic dysfunction (aOR 5, 95% CI [1.35-9.57] were independently associated with PAH.

conclusionOne third of hemodialysis patients exhibit PAH, which is independently associated with low socioeconomic status (unsecured funding, vascular access change) and cardiovascular complications (arrhythmia, diastolic dysfunction).

Indexed as

Renal DialysisBlood Chemical AnalysisCross-Sectional StudiesDemocratic Republic of the CongoEchocardiographyFemaleHumansKidney Failure, ChronicLogistic ModelsMaleMiddle AgedPrevalencePulmonary Arterial HypertensionSocial ClassCardiovascular diseaseHemodialysisPulmonary hypertensionSystolic pulmonary arterial pressure

Identifiers

PMID33148221
PMCPMC7640388
OpenAlexW3097717434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.