Evidence map›Paper›PMID 33148217›Full record

SynthesisBMC oral health2020

Efficacy evaluation of photodynamic therapy for oral lichen planus: a systematic review and meta-analysis.

Yuqing He, Jiaxin Deng, Yi Zhao, Huiqian Tao, Hongxia Dan, Hao Xu, Qianming Chen

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. [Treatment of oral lichen planus-a review].Dermatologie (Heidelberg, Germany) · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. What can we learn from treatments of oral lichen planus?Frontiers in cellular and infection microbiology · 2024
    Review
  14. Oral Lichen Planus: An Update on Diagnosis and Management.American journal of clinical dermatology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuqing HeState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Jiaxin DengState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Yi ZhaoState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Huiqian TaoState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Hongxia DanState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Hao XuState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China. xhstatis@hotmail.com.ORCID 0000-0002-5665-0139
Qianming ChenState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, No. 14, Sec.3, Ren Min Nan Road, Chengdu, 610041, Sichuan, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhotodynamic therapy (PDT) is a new option for oral lichen planus (OLP) management; however, there are different opinions on the efficacy of PDT for OLP. The aim of this study was to comprehensively assess the efficacy of PDT in the treatment of OLP and compare PDT with steroid therapy.

methodsA systematic review and meta-analysis were conducted to assess the curative effect of PDT. Five electronic databases were searched, PubMed, Web of Science, the Cochrane Library, Embase, and EBSCO up to 1 December, 2019. Random and fixed effects models for pooled estimates calculation were used and the Meta package of R was applied.

resultsPooled estimates revealed that, after PDT, the lesion size decreased by 1.53 cm

conclusionThis systematic review indicates that PDT is an effective treatment modality for the management of OLP. PDT is as effective as topical corticosteroid in the treatment of OLP and could be used for cases resistant to steroids or when steroids are contraindicated.

Indexed as

Lichen Planus, OralPhotochemotherapyHumansLasers, SemiconductorTreatment OutcomeEfficacy evaluationMeta-analysisOral lichen planusPhotodynamic therapy

Identifiers

PMID33148217
PMCPMC7640434
OpenAlexW3095935944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.