Evidence map›Paper›PMID 33148215›Full record

ArticleBMC geriatrics2020

Short- and long-term outcomes of laparoscopic surgery for colorectal cancer in the elderly aged over 80 years old versus non-elderly: a retrospective cohort study.

Yoshitake Ueda, Norio Shiraishi, Takahide Kawasaki, Tomonori Akagi, Shigeo Ninomiya, Hidefumi Shiroshita, Tsuyoshi Etoh, Masafumi Inomata

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06609551 (ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06609551 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study

TypeinterventionalSponsorZhejiang Cancer HospitalRan2024 to 2034Enrolled312ConditionsColon Cancer, Colon Cancer (Stage II &Amp, Amp, AmpArms6-month adjuvant chemotherapy with 5-FU monotherapy, XELOX intensive treatment group
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yoshitake UedaDepartment of Comprehensive Surgery for Community Medicine, Oita University Faculty of Medicine, Hasama-machi, Oita, 879-5593, Japan.
Norio ShiraishiDepartment of Comprehensive Surgery for Community Medicine, Oita University Faculty of Medicine, Hasama-machi, Oita, 879-5593, Japan. norioh@oita-u.ac.jp.ORCID 0000-0003-2187-3989
Takahide KawasakiDepartment of Comprehensive Surgery for Community Medicine, Oita University Faculty of Medicine, Hasama-machi, Oita, 879-5593, Japan.
Tomonori AkagiDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Oita, Japan.
Shigeo NinomiyaDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Oita, Japan.
Hidefumi ShiroshitaDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Oita, Japan.
Tsuyoshi EtohDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Oita, Japan.
Masafumi InomataDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Oita, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, colorectal cancer has increased in elderly patients worldwide, with laparoscopic colorectal surgery increasing in elderly patients with colorectal cancer. However, whether laparoscopic colorectal surgery is an optimal procedure for colorectal cancer in the elderly remains unclear. This study aimed to verify safety and curability of laparoscopic colorectal surgery in elderly patients ≥80 years old.

methodsPatients undergoing curative colorectal surgery from 2006 to 2014 were enrolled and classified into the laparoscopic surgery in elderly patients aged ≥80 years (LAC-E) group, open surgery in elderly patients (OC-E) group, and laparoscopic surgery in non-elderly patients (LAC-NE) group. Short- and long-term outcomes were compared between these groups.

resultsThe LAC-E, OC-E, and LAC-NE groups comprised 85, 25, and 358 patients, respectively. Intraoperative blood loss and incidence of postoperative complications were significantly lower in the LAC-E versus OC-E group (97 vs. 440 mL, p < .01 and 14% vs. 32%, p < .05, respectively). Long-term outcomes were not different between these two groups. Operation time was significantly shorter in the LAC-E versus LAC-NE group (249 vs. 288 min, p < .01). Intraoperative blood loss and postoperative complications were similar between the groups. Although the 5-year overall survival rate in the LAC-E group was lower than that in the LAC-NE group (64% vs. 80%, p < .01), there was no difference in 5-year disease-specific survival between the groups.

conclusionLaparoscopic colorectal surgery is technically and oncologically safe for colorectal cancer in the elderly as well as the non-elderly and can be an optimal procedure for colorectal cancer in the elderly.

Indexed as

Colonic NeoplasmsColorectal NeoplasmsLaparoscopyAgedAged, 80 and overHumansMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeColorectal cancerCurabilityElderlyLaparoscopic surgerySafety

Identifiers

PMID33148215
PMCPMC7641812
OpenAlexW3097090949

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.