Evidence map›Paper›PMID 33148206›Full record

ArticleBMC pregnancy and childbirth2020

Associated factors of secondary sex ratio of offspring in assisted reproductive technology: a cross-sectional study in Jilin Province, China.

Mohan Wang, Xiangyin Liu, Han Zhang, Leilei Li, Ruizhi Liu, Hongguo Zhang, Yang Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohan WangCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Xiangyin LiuCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Han ZhangCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Leilei LiCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Ruizhi LiuCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Hongguo ZhangCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China.
Yang YuCenter of Reproductive Medicine, Center of Prenatal Diagnosis, the First Hospital, Jilin University, 71 Xinmin Street, Changchun, Jilin, 130021, China. yuyang0351@126.com.ORCID http://orcid.org/0000-0002-6555-7390
Jilin University · CN

Funding

Finance Department Health Special Project of Jilin Province, China. JLSCZD2019-022
6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the secondary sex ratio (SSR) of offspring in assisted reproduction technology (ART) in Jilin Province, China, and to analyse the influencing factors associated with SSR.

methodsA cross-sectional study of 3833 babies including singletons and twins born to 2990 couples treated by ART between May 2011 and December 2018 was performed.

resultsThe main outcomes of this study were that the SSR of ART babies in Jilin Province was 50.64% and the SSR was associated with fertilization methods (p < 0.05). Comparing to in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI) (OR = 0.808, 95%CI: 0.681-0.958) decreased the percentage of male babies.

conclusionsThis study suggests that the SSR of ART births in Jilin Province was lower than the normal level and ICSI had a significant effect on SSR. Though we need more samples to study in the future, we still need to think about the impact of ICSI on SSR in ART.

Indexed as

Sex RatioAdultChinaCross-Sectional StudiesEmbryo TransferFemaleHumansInfertilityLive BirthMaleMaternal AgeMiddle AgedPaternal AgePregnancyRetreatmentSperm Injections, IntracytoplasmicAssisted reproduction technologyIntracytoplasmic sperm injectionSecondary sex ratio

Identifiers

PMID33148206
PMCPMC7640482
OpenAlexW3095684940

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.