Evidence map›Paper›PMID 33147876›Full record

ArticleBiomolecules2020

Antitumour Activity of the Ribonuclease Binase from

Islam Saber Ead Mohamed, Aleksandra V Sen'kova, Alsu I Nadyrova, Innokenty A Savin, Andrey V Markov, Vladimir A Mitkevich, Aleksander A Makarov, Olga N Ilinskaya, Nadezhda L Mironova, Marina A Zenkova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. SoloxoloneMolecules (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Islam Saber Ead MohamedInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0002-1710-3925
Aleksandra V Sen'kovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Alsu I NadyrovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
Innokenty A SavinInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Andrey V MarkovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0001-7569-9555
Vladimir A MitkevichEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0002-1517-1983
Aleksander A MakarovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.
Olga N IlinskayaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia.
Nadezhda L MironovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Marina A ZenkovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0003-4044-1049
Institute of Chemical Biology and Fundamental Medicine · RUEngelhardt Institute of Molecular Biology · RUKazan Federal University · RUNovosibirsk State University · RU

Funding

Russian Foundation for Basic Research 17-00-00059Russian Foundation for Basic Research 17-00-00060Russian Foundation for Basic Research 17-00-00061
6 · The paper itself

Abstract

The important role of miRNA in cell proliferation and differentiation has raised interest in exogenous ribonucleases (RNases) as tools to control tumour-associated intracellular and extracellular miRNAs. In this work, we evaluated the effects of the RNase binase from

Indexed as

AnimalsApoptosisBacillus pumilusCell DifferentiationCell ProliferationEndoribonucleasesGene Expression Regulation, NeoplasticHumansLiver NeoplasmsLymphoma, Non-HodgkinMiceMicroRNAsRibonucleasesEndoribonucleasesMicroRNAsMIRN31 microRNA, humanRibonucleasesribonuclease T(2)antitumour activitybinasecytotoxicitymiRNAsRNasestumour models

Identifiers

PMID33147876
PMCPMC7692507
OpenAlexW3095624218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.