Evidence map›Paper›PMID 33147761›Full record

ArticleNanomaterials (Basel, Switzerland)2020

PLGA Membranes Functionalized with Gelatin through Biomimetic Mussel-Inspired Strategy.

Irene Carmagnola, Valeria Chiono, Gerardina Ruocco, Annachiara Scalzone, Piergiorgio Gentile, Paola Taddei, Gianluca Ciardelli

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  10. Biomimetic design of bioartificial scaffolds for theFrontiers in bioengineering and biotechnology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Irene CarmagnolaDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0001-6080-317X
Valeria ChionoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0003-2067-7732
Gerardina RuoccoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.
Annachiara ScalzoneSchool of Engineering, Newcastle University, Claremont road, Newcastle upon Tyne NE1 7RU, UK.ORCID 0000-0002-2354-8509
Piergiorgio GentileSchool of Engineering, Newcastle University, Claremont road, Newcastle upon Tyne NE1 7RU, UK.
Paola TaddeiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-8478-4508
Gianluca CiardelliDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0003-0199-1427
Politecnico di Torino · ITNewcastle University · GBUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospun membranes have been widely used as scaffolds for soft tissue engineering due to their extracellular matrix-like structure. A mussel-inspired coating approach based on 3,4-dihydroxy-DL-phenylalanine (DOPA) polymerization was proposed to graft gelatin (G) onto poly(lactic-co-glycolic) acid (PLGA) electrospun membranes. PolyDOPA coating allowed grafting of gelatin to PLGA fibers without affecting their bulk characteristics, such as molecular weight and thermal properties. PLGA electrospun membranes were dipped in a DOPA solution (2 mg/mL, Tris/HCl 10 mM, pH 8.5) for 7 h and then incubated in G solution (2 mg/mL, Tris/HCl 10 mM, pH 8.5) for 16 h. PLGA fibers had an average diameter of 1.37 ± 0.23 µm. Quartz crystal microbalance with dissipation technique (QCM-D) analysis was performed to monitor DOPA polymerization over time: after 7 h the amount of deposited polyDOPA was 71 ng/cm

Indexed as

biomimetic functionalizationDOPAelectrospinningPLGAsurface modification

Identifiers

PMID33147761
PMCPMC7692787
OpenAlexW3097928825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.