Evidence map›Paper›PMID 33147738›Full record

ArticleMicroorganisms2020

The Domestic Environment and the Lung Mycobiome.

Esther Rubio-Portillo, David Orts, Eleuterio Llorca, Cleofé Fernández, Josefa Antón, Consuelo Ferrer, Beatriz Gálvez, Violeta Esteban, Elena Revelles, Carlos Pérez-Martín and 6 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Interactions between Bacteria andJournal of fungi (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Importance of Clinical Isolates inJournal of fungi (Basel, Switzerland) · 2023
    Review
  11. Journal of fungi (Basel, Switzerland) · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Esther Rubio-PortilloDepartment of Physiology, Genetics and Microbiology, University of Alicante, Sant Vicent del Raspeig, 03690 Alicante, Spain.ORCID 0000-0002-5602-5333
David OrtsPneumology Service, General University Hospital, Elda, 03600 Alicante, Spain.
Eleuterio LlorcaPneumology Service, General University Hospital, Elda, 03600 Alicante, Spain.
Cleofé FernándezRespiratory Department, General University Hospital, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), 03010 Alicante, Spain.
Josefa AntónDepartment of Physiology, Genetics and Microbiology, University of Alicante, Sant Vicent del Raspeig, 03690 Alicante, Spain.
Consuelo FerrerMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Beatriz GálvezPneumology Department, Vinalopó University Hospital, Elche 03293 Alicante, Spain.
Violeta EstebanRespiratory Department, University Hospital of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-3836-5884
Elena RevellesMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Carlos Pérez-MartínMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Enrique Gómez-ImbernónMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Jorge AdsuarMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Pedro PiquerasMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.
Beatriz AmatPneumology Department, Vinalopó University Hospital, Elche 03293 Alicante, Spain.
José FrancoRespiratory Department, University Hospital of Valencia, 46010 Valencia, Spain.
María Francisca ColomMedical Mycology Laboratory, Department of Plant Production and Microbiology, Institute for Healthcare and Biomedical Research of Alicante (ISABIAL), Campus of Sant Joan d'Alacant, University Miguel Hernández, 03550 Alicante, Spain.ORCID 0000-0002-8672-5429
Universitat de Miguel Hernández d'Elx · ESHospital Clínico Universitario de Valencia · ESHospital General de Elda · ESHospital Universitario del Vinalopó · ESUniversity of Alicante · ESHospital General Universitario de Alicante Doctor Balmis · ES

Funding

Spanish Association for Respiratory Diseases (SEPAR) RESPIRA PII026/2016
6 · The paper itself

Abstract

This study analyzes the relationship between the mycobiome of the Lower Respiratory Tract (LRT) and the fungi in the domestic environment. Samples studied consisted of Broncho-Alveolar Lavage (BAL) from 45 patients who underwent bronchoscopy for different diagnostic purposes, and dust and air from the houses (ENV) of 20 of them (44.4%). Additionally, five bronchoscopes (BS) were also analyzed and negative controls were included for every procedure. All samples were processed for DNA extraction and cultures, which were performed in Sabouraud Dextrose and Potato Dextrose Agar. The fungal Internal Transcribed Spacer (ITS2) was sequenced by the Solexa/Illumina system and sequences were analyzed by QIIME 1.8.0 and compared with the UNITE Database for identification. The similarity between the two fungal communities (BAL and ENV) for a specific patient was assessed via the percentage of coincidence in the detection of specific operational taxonomic units (OTUs), and about 75% of co-occurrence was detected between the mycobiome of the LRT and the houses. Cultures confirmed the presence of the core mycobiome species. However, the low rate of isolation from BAL suggests that most of its mycobiome corresponds to non-culturable cells. This likely depends on the patient's immune system activity and inflammatory status.

Indexed as

bronco-alveolar lavagefungihouse dustlower respiratory tractmycobiomemycobiota

Identifiers

PMID33147738
PMCPMC7693370
OpenAlexW3097287408

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.