Evidence map›Paper›PMID 33147727›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Aminodextran Coated CoFe

Sumera Khizar, Nasir M Ahmad, Naveed Ahmed, Sadia Manzoor, Muhammad A Hamayun, Nauman Naseer, Michele K L Tenório, Noureddine Lebaz, Abdelhamid Elaissari

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Biocompatible gelatin-coated ferrite nanoparticles: A magnetic approach to advanced drug delivery.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  6. Article
  7. Newly Synthesized CoFeInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sumera KhizarPolymer Research Lab, School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), H-12 Sector, Islamabad 44000, Pakistan.
Nasir M AhmadPolymer Research Lab, School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), H-12 Sector, Islamabad 44000, Pakistan.
Naveed AhmedDepartment of Pharmacy, Quaid i Azam University, Islamabad 45320, Pakistan.ORCID 0000-0002-4780-9945
Sadia ManzoorDepartment of Physics, COMSAT University, Islamabad 44000, Pakistan.
Muhammad A HamayunDepartment of Physics, COMSAT University, Islamabad 44000, Pakistan.
Nauman NaseerDepartment of Cardiology, King Edward Medical University, Lahore 5400, Pakistan.
Michele K L TenórioDepartment of Chemistry, State University of Ponta Grossa, Av. Gen. Carlos Cavalcanti, 4748, CEP 84030-900 Ponta Grossa, Paraná, Brazil.ORCID 0000-0003-3669-7025
Noureddine LebazUniv Lyon, University Claude Bernard Lyon-1, CNRS, LAGEPP-UMR 5007, F-69622 Lyon, France.ORCID 0000-0001-7116-8554
Abdelhamid ElaissariUniv Lyon, University Claude Bernard Lyon-1, CNRS, LAGEPP-UMR 5007, F-69622 Lyon, France.ORCID 0000-0002-2151-9894

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico ( CNPqHEC grant No. 9046Higher Education Commission (HEC) NRPU 3526 and 6020
6 · The paper itself

Abstract

Aminodextran (AMD) coated magnetic cobalt ferrite nanoparticles are synthesized via electrostatic adsorption of aminodextran onto magnetic nanoparticles and their potential theranostic application is evaluated. The uncoated and aminodextran-coated nanoparticles are characterized to determine their hydrodynamic size, morphology, chemical composition, zeta potential and magnetization. The aminodextran containing cobalt ferrite nanoparticles of nanometer size are positively charged in the pH range from 3 to 9 and exhibit saturation magnetization of 50 emu/g. The magnetic resonance imaging (MRI) indicates capability for diagnostics and a reduction in intensity with an increase in nanoparticle amount. The hyperthermia capability of the prepared particles shows their potential to generate suitable local heat for therapeutic purposes. There is a rise of 7 °C and 9 °C at 327 kHz and 981 kHz respectively and specific absorption rates (SAR) of aminodextran-coated nanoparticles are calculated to be 259 W/g and 518 W/g at the given frequencies larger than uncoated nanoparticles (0.02 W/g). The development of novel aminodextran coated magnetic cobalt ferrite nanoparticles has significant potential to enable and improve personalized therapy regimens, targeted cancer therapies and ultimately to overcome the prevalence of nonessential and overdosing of healthy tissues and organs.

Indexed as

adsorptionfunctionalizationin vitro diagnosismagnetic particlesMRItheranostic

Identifiers

PMID33147727
PMCPMC7692372

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.