Evidence map›Paper›PMID 33147705›Full record

Trial reportNutrients2020

Impact of Long-Term Supplementation with Fish Oil in Individuals with Non-Alcoholic Fatty Liver Disease: A Double Blind Randomized Placebo Controlled Clinical Trial.

Kátia Cansanção, Marta Citelli, Nathalie Carvalho Leite, María-Carmen López de Las Hazas, Alberto Dávalos, Maria das Graças Tavares do Carmo, Wilza Arantes Ferreira Peres

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kátia CansançãoInstitute of Nutrition Josué de Castro of Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21.941-902, Brazil.
Marta CitelliInstituto de Nutrição, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20559-900, Brazil.
Nathalie Carvalho LeiteDepartment of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine of UFRJ, Rio de Janeiro 21.941-902, Brazil.
María-Carmen López de Las HazasLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain.ORCID 0000-0001-8199-6724
Alberto DávalosLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies (IMDEA)-Food, CEI UAM+CSIC, 28049 Madrid, Spain.
Maria das Graças Tavares do CarmoInstitute of Nutrition Josué de Castro of Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21.941-902, Brazil.ORCID 0000-0003-1376-1098
Wilza Arantes Ferreira PeresInstitute of Nutrition Josué de Castro of Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21.941-902, Brazil.ORCID 0000-0003-0269-5363
Universidade Federal do Rio de Janeiro · BRMadrid Institute for Advanced Studies · ESHospital Universitário Clementino Fraga Filho · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

Agencia Estatal de Investigación and European FEDER Funds PID2019-109369RB-I00 and RTI2018-093873-A-I00Apoio às Instituições de Ensino e Pesquisa Sediadas no Rio de Janeiro E-26/010.100978/2018[Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (Young Scientist of Our State) E-26/203.250/2017Coordination for the Improvement of Higher Education Personnel] (Print) nº.41/2017This research was funded by Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), .
6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a chronic disease affecting up to 25% of the population worldwide. n-3 long-chain polyunsaturated fatty acids (n-3 PUFA) have been associated with improved clinical parameters of NAFLD. Our purpose was to conduct a pilot study to evaluate the effects of n-3 PUFA supplementation in a randomized, double-blind, placebo-controlled clinical study performed on NAFLD individuals diagnosed by ultrasound. Patients received n-3 PUFA (

Indexed as

Dietary SupplementsAgedAlkaline PhosphataseDocosahexaenoic AcidsDouble-Blind MethodDrug Administration ScheduleEicosapentaenoic AcidFatty Acids, Omega-3FemaleFish OilsHumansMaleMicroRNAsMiddle AgedNon-alcoholic Fatty Liver DiseasePilot ProjectsAlkaline PhosphataseDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3Fish OilsMicroRNAsMIRN122 microRNA, humanalkaline phosphatasefish oilliver fibrosismiR-122miRNANAFLDpolyunsaturated fatty acid

Identifiers

PMID33147705
PMCPMC7693661
OpenAlexW3097736804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.