Evidence map›Paper›PMID 33147687›Full record

ArticleDentistry journal2020

Adjunctive Antiseptic Irrigation of Periodontal Pockets: Effects on Microbial and Cytokine Profiles.

Anton Vitt, Andrei Babenka, Elisabeth A Boström, Anders Gustafsson, Ronaldo Lira Junior, Veronica Slizen, Timo Sorsa, Taina Tervahartiala, Kåre Buhlin

Abstract read
In one paragraph

Article in Dentistry journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anton VittDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.ORCID 0000-0002-5689-6892
Andrei BabenkaDepartment of Bioorganic Chemistry, Belarusian State Medical University, 220045 Minsk, Belarus.ORCID 0000-0002-5513-970X
Elisabeth A BoströmDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.ORCID 0000-0003-1788-7501
Anders GustafssonDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.
Ronaldo Lira JuniorDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.
Veronica SlizenDepartment of Microbiology, Virology and Immunology, Belarusian State Medical University, 220045 Minsk, Belarus.
Timo SorsaDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.
Taina TervahartialaDepartment of Oral and Maxillofacial Diseases, Institute of Dentistry, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0001-8817-896X
Kåre BuhlinDepartment of Dental Medicine, Division of Periodontology, Karolinska Institutet, 14152 Huddinge, Sweden.

Funding

Helsingin Yliopiston Tiedesäätiö TYH 2016251Helsingin Yliopiston Tiedesäätiö TYH 2017251Swedish Institute Visby Programme 00742/2010
6 · The paper itself

Abstract

To evaluate the effect of adjunctive antiseptic irrigation of periodontal pockets on microbial and cytokine profiles. Fifty-nine patients with severe periodontitis were allocated to one of three groups for scaling and root planing facilitated with different adjunctive antiseptics: 1% polyhexamethyleneguanidine phosphate (PHMG-P) (n = 19), 0.2% chlorhexidine (CHX) (n = 21) or distilled water (n = 19). Gingival crevicular fluid and subgingival bacterial samples were collected at baseline, and at 2 weeks, and 1 and 4 months. The levels of interleukin (IL)-1β, IL-8, IL-10, and IL-17A, matrix metalloproteinase (MMP)-8,

Indexed as

chlorhexidineinflammationirrigationperiodontitispolyhexamethylene guanidine phosphate

Identifiers

PMID33147687
PMCPMC7712355

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.