Evidence map›Paper›PMID 33147656›Full record

ArticleThe Journal of clinical psychiatry2020

Differences in Prescription Stimulant Misuse Motives Across Adolescents and Young Adults in the United States.

Ty S Schepis, Jason A Ford, Timothy E Wilens, Christian J Teter, Sean Esteban McCabe

Abstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ty S SchepisDepartment of Psychology, Texas State University, 601 University Drive, San Marcos, TX 78666. schepis@txstate.edu.
Jason A FordDepartment of Sociology, University of Central Florida, Orlando, Florida, USA.
Timothy E WilensMassachusetts General Hospital, Boston, Massachusetts, USA.
Christian J TeterResearch Pharmacy Core, McLean Hospital, Belmont, Massachusetts, USA.
Sean Esteban McCabeCenter for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Optimized Interventions to Prevent Opioid Use Disorder among Adolescents and Young Adults in the Emergency DepartmentUH3DA050173 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BONAR, ERIN E., WALTON, MAUREEN A · 2020 to 2021
$5.8M
Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Prescription Drug Misuse Characteristics in Adolescents and Young Adults: Influence of School EnrollmentR01DA043691 · NIDA · TEXAS STATE UNIVERSITY · PI TY Stephen SCHEPIS · 2017 to 2026
$1.8M
Discrimination, Stress and Substance Use Disorder among Sexual Minority Adults: A Secondary Analysis of NESARC-IIIR01DA043696 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2017 to 2019
$1.1M
Does Treating Young Persons Psychopathology Prevent the Onset of Opioid and other Substance Use Disorders?UG3DA050252 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI WILENS, TIMOTHY E, YULE, AMY · 2019 to 2019
$749k
NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA043691NIDA NIH HHS R01 DA043696NIDA NIH HHS UG3 DA050252NIDA NIH HHS UH3 DA050173
6 · The paper itself

Abstract

objectiveWhile prescription stimulant misuse (PSM) is common in adolescents and young adults (AYAs), PSM motives are poorly understood. This study examined a number of PSM motives across the AYA age spectrum using the 2015-2018 National Survey on Drug Use and Health.

methodsIn all, 86,918 AYAs (aged 14-25 years) were included. Individual PSM motives (eg, to study) and motive categories (ie, cognitive enhancement only, recreational only, weight loss only, and combined motives) were examined by age. Logistic regression models examined links between individual motives or motive categories and educational status, substance use, DSM-IV substance use disorders (SUD), and mental health correlates.

resultsSignificant differences were found across AYAs in cognitive enhancement only (14 years = 40.4%; 24 and 25 years = 71.2%; P < .0001) and recreational only (14 years = 25.8%; 24 and 25 years = 9.8%; P < .0001) or combined PSM motives, (14 years = 32.3%; 24 and 25 years = 18.0%; P = .008); college students and graduates had particularly high rates of cognitive enhancement only (college = 78.2%; graduates = 74.7%; non-college = 63.5%). Recreational-only and combined motives were significantly elevated in AYAs with any past-year SUD, especially to get high (78%-136% higher in those with SUD; P ≤ .001). While any PSM was associated with higher odds of SUD and mental health outcomes, including suicidal ideation, odds were highest for recreational or combined motives.

conclusionsCognitive enhancement with PSM occurs more often in young adults compared to adolescents, college students endorse more cognitive enhancement than those not in school, and the presence of any PSM in AYAs is linked to more substance use, suicidal ideation, and other psychopathology. PSM prevention in adolescents as well as screening and intervention among AYA is highly recommended.

Indexed as

Central Nervous System StimulantsMotivationNootropic AgentsSuicidal IdeationAdultAge FactorsFemaleHealth SurveysHumansMalePrescription Drug MisuseRecreational Drug UseStudentsUnited StatesUniversitiesYoung AdultCentral Nervous System StimulantsNootropic Agents

Identifiers

PMID33147656
PMCPMC7883338

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.