ArticleAnnals of the New York Academy of Sciences2021
Changes in hemoglobin levels with age and altitude in preschool-aged children in Peru: the assessment of two individual-based national databases.
Article in Annals of the New York Academy of Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Higher Prevalence of Cognitive Impairment in Residents of High-Altitude Regions.Oxygen (Basel, Switzerland) · 2026Article
- Comparison of Red Blood Cell Features in Israeli Circassians: The Possible Effect of Residential Altitude.Rambam Maimonides medical journal · 2026Article
- Implications of changes in WHO haemoglobin elevation adjustment guidelines on global, regional, and national anaemia burden, 1990-2023: a population-based modelling study.The Lancet. Haematology · 2026Article
- Reference Intervals for Hemoglobin and Hematocrit Adjusted for Altitude, Sex, and Age: A Big Data-Based Study in the Colombian Population.Medical sciences (Basel, Switzerland) · 2026Article
- Anemia crisis among children in Peru: a scoping review.Revista panamericana de salud publica = Pan American journal of public health · 2026Review
- Political instability and child anemia in Peru: a national interrupted time-series analysis, 2006-2024.Frontiers in public health · 2026Article
- Observational
- Article
- Article
- Micronutrient Status and Other Correlates of Hemoglobin among Children with Stunting: A Cross-Sectional Study in Uganda.Nutrients · 2023Article
- A Critical Analysis of the Automated Hematology Assessment in Pregnant Women at Low and at High Altitude: Association between Red Blood Cells, Platelet Parameters, and Iron Status.Life (Basel, Switzerland) · 2022Article
- The New WHO Cut-off Point for Defining High-altitude Anemia may be Inadequate.Inquiry : a journal of medical care organization, provision and financingArticle
- One-Year Daily Micronutrient Supplementation and Anemia Prevalence Among Mildly Stunted Infants in Bhaktapur, Nepal.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
According to the World Health Organization, the cutoff hemoglobin (Hb) value for defining anemia is 11 g/dL in preschool-aged children, and Hb measurements should be corrected above an altitude of 1000 meters. This study sought to determine the altitude at which the Hb value increases compared with that at sea level, Hb changes with age and region in Peru, the prevalence of anemia according to three different models used to correct Hb for altitude, and the association of the Hb value with stunting. Two individual-based Peruvian national databases were analyzed. Hb increased from an altitude of 375 meters. Hb concentration was lower at younger ages and higher at older ages. The increase in Hb with increasing altitude was lower in southern Peru. Implementing the different models for Hb measurement correction resulted in a higher and lower prevalence of anemia at altitudes >2500 and <2500 m, respectively, using the CDC adjustment. In children aged 6-23 months, the rate of stunting was lower in those with an Hb level of 10-12 g/dL (including mild anemia). In conclusion, the adjustment of Hb values for altitude should be considered before 1000 m and reference ranges should be adjusted to smaller groups of children instead of the same reference range for children aged 6-59 months.
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