ArticleJournal of cachexia, sarcopenia and muscle2020
Normative values of muscle strength across ages in a 'real world' population: results from the longevity check-up 7+ project.
Article in Journal of cachexia, sarcopenia and muscle, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07362329 (Use of Resistive Exercise Snacks to Improve Upper Body Fitness in Graduate Students), which is not on this map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Resistive Exercise Snacks to Improve Upper Body Fitness in Graduate Students
Who cites it
64 citing papers in PubMed, 104 citations in OpenAlex.
- Trial
- Article
- Reference Values for Maximal Isometric Handgrip and Pinch Strength in Healthy Italian Adults Without Occupational Biomechanical Overload.La Medicina del lavoro · 2026Article
- Reference values for the five-times-sit-to-stand test: a pooled analysis including 45,470 participants from 14 countries.GeroScience · 2026Article
- Reference values for gait speed, five-times-sit-to-stand test, balance, and handgrip strength: analysis of data from the English Longitudinal Study of Ageing.GeroScience · 2026Article
- Assessment of muscle wasting in intensive care unit patients with and without COVID-19 using ultrasound imaging and bioimpedance analysis.BMC anesthesiology · 2026Article
- Long-term musculoskeletal impacts on the functionality of Brazilian patients after SARS-CoV-2: assessment through telehealth.Frontiers in rehabilitation sciences · 2026Article
- From homeostasis to pathology, organelle-specific autophagy in skeletal muscle: a PRISMA-ScR scoping review.Frontiers in physiology · 2026Review
- Effects of Adapted Physical Activity Programs on Body Composition and Sports Performance in a Patient with Parkinson's Disease: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- Effects of a One-Year Multicomponent Exercise Program on Community-Dwelling Older Adults at Risk of Sarcopenic Obesity.Journal of clinical medicine · 2025Article
- Association between grip and core muscle strength in people with axial spondyloarthritis and healthy controls.BMC rheumatology · 2025Article
- Associations between sarcopenia operationalized using muscle strength or power and health-related parameters.The Journal of frailty & aging · 2025Article
- Development and Validation of Quantile Regression Forests for Prediction of Reference Quantiles in Handgrip and Chair-Stand Test.Journal of cachexia, sarcopenia and muscle · 2025Article
- Reference Values of Handgrip and Lower Extremity Strength for Vietnamese Men and Women: The Vietnam Osteoporosis Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- Cross-sectional associations between dietary intake of polyunsaturated fatty acids, physical function, and sarcopenia in community-dwelling older adults.The journal of nutrition, health & aging · 2025Article
- Effectiveness of the active senior program in preparing for physical deterioration and quality aging among pre-older adults in Prachin Buri Province, Thailand: A quasi-experimental study.Belitung nursing journal · 2025Article
- Association of calf circumference with osteoporosis and hip fracture in middle-aged and older adults: a secondary analysis.BMC musculoskeletal disorders · 2024Article
- Muscle quality index comparisons between Hispanics and non-Hispanic Caucasians using dual energy X-ray absorptiometry and handgrip strength.European journal of clinical nutrition · 2024Article
- Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults.Nutrients · 2024Article
- Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow muscle strength is a powerful predictor of negative health-related events and a key component of sarcopenia. The lack of normative values for muscle strength across ages hampers the practical appraisal of this parameter. The aim of the present study was to produce normative values for upper and lower extremity muscle strength across a wide spectrum of ages, in a large sample of community-dwellers recruited in the Longevity check-up (Lookup) 7+ project.
methodsLookup 7+ is an ongoing project that started in June 2015 and conducted in unconventional settings (i.e. exhibitions, malls, and health promotion campaigns) across Italy with the aim of fostering the adoption of healthy lifestyles in the general population. Candidate participants are eligible for enrolment if they are 18+ years and provide written informed consent. Upper and lower extremity muscle strength is assessed by handgrip strength and five-repetition chair-stand [5 × sit-to-stand (STS)] tests, respectively. Cross-sectional centile and normative values for handgrip strength and 5 × STS tests from age 18 to 80+ years were generated for the two genders. Smoothed normative curves for the two tests were constructed for men and women using the lambda-mu-sigma method.
resultsFrom 1 June 2015 to 30 May 2019, 11 448 participants were enrolled. The mean age of participants was 55.6 years (standard deviation: 11.5 years; range: 18-98 years), and 6382 (56%) were women. Normative values for handgrip strength and the 5 × STS test, both absolute and normalized by body mass index, were obtained for men and women, stratified by age groups. Values of upper and lower extremity muscle strength across ages identified three periods in life: an increase to peak in young age and early adulthood (18-24 years), preservation through midlife (25-44 years), and a decline from midlife onwards (45+ years).
conclusionsOur study established age-specific and gender-specific percentile reference values for handgrip strength and the 5 × STS test. The normative curves generated can be used to interpret the assessment of muscle strength in everyday practice for the early detection of individuals with or at risk of sarcopenia.
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