Evidence map›Paper›PMID 33147361›Full record

ArticleBrain pathology (Zurich, Switzerland)2021

Primary age-related tauopathy (PART) in the general autopsy setting: Not just a disease of the elderly.

William O Humphrey, Rachel Martindale, William W Pendlebury, John C DeWitt

Abstract readLetter
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Primary age-related tauopathy.Acta neuropathologica · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Tauopathies: new perspectives and challenges.Molecular neurodegeneration · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William O HumphreyDepartment of Pathology and Laboratory Medicine, The University of Vermont Medical Center, Burlington, VT, USA.
Rachel MartindaleDepartment of Pathology and Laboratory Medicine, The University of Vermont Medical Center, Burlington, VT, USA.
William W PendleburyDepartment of Pathology and Laboratory Medicine, The University of Vermont Medical Center, Burlington, VT, USA.
John C DeWittDepartment of Pathology and Laboratory Medicine, The University of Vermont Medical Center, Burlington, VT, USA.ORCID 0000-0002-0343-2656

Funding

Amyotrophic Lateral Sclerosis Association 18-IIA-437
6 · The paper itself

Abstract

Primary age-related tauopathy (PART) is generally considered a diagnosis of the elderly. In this letter, the authors present data showing that the pathologic changes of PART can occur in the general autopsy population significantly earlier than largely reported in the recent literature, particularly in woman.

Indexed as

AdultAgedAged, 80 and overAutopsyFemaleHumansMaleMiddle AgedTauopathiesAlzheimerdementianeurodegenerativePARTTau

Identifiers

PMID33147361
PMCPMC8018030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.