Evidence map›Paper›PMID 33147073›Full record

Trial reportJCO clinical cancer informatics2020

Wearable Respiratory Monitoring and Feedback for Chronic Pain in Adult Survivors of Childhood Cancer: A Feasibility Randomized Controlled Trial From the Childhood Cancer Survivor Study.

Nicole M Alberts, Wendy M Leisenring, Jessica S Flynn, Jillian Whitton, Todd M Gibson, Lindsay Jibb, Aaron McDonald, James Ford, Neema Moraveji, Blake F Dear and 4 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JCO clinical cancer informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Nicole M AlbertsSt Jude Children's Research Hospital, Memphis, TN.
Wendy M LeisenringFred Hutchinson Cancer Research Center, Seattle, WA.ORCID 0000-0001-7405-0906
Jessica S FlynnSt Jude Children's Research Hospital, Memphis, TN.
Jillian WhittonFred Hutchinson Cancer Research Center, Seattle, WA.
Todd M GibsonNational Institutes of Health, Bethesda, MD.ORCID 0000-0002-8718-699X
Lindsay JibbThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-6995-2825
Aaron McDonaldSt Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-4240-1131
James FordSt Jude Children's Research Hospital, Memphis, TN.
Neema MoravejiSpire Health, San Francisco, CA.
Blake F DearMacquarie University, Sydney, New South Wales, Australia.
Kevin R KrullSt Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-0476-7001
Leslie L RobisonSt Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-7460-8578
Jennifer N StinsonThe Hospital for Sick Children, Toronto, Ontario, Canada.
Gregory T ArmstrongSt Jude Children's Research Hospital, Memphis, TN.
St. Jude Children's Research Hospital · USFred Hutch Cancer Center · USHospital for Sick Children · CAMacquarie University · AUNational Institutes of Health · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
NCI NIH HHS P30 CA021765NCI NIH HHS U24 CA055727
6 · The paper itself

Abstract

purposeApproximately 40% of childhood cancer survivors experience chronic pain, with many also reporting pain-related disability. Given associations established in the general population among respiration, anxiety, and pain, continuous tracking and feedback of respiration may help survivors manage pain.

methodsA feasibility, nonblinded, randomized controlled trial (RCT) comparing wearable respiratory monitoring with a control group examined feasibility, acceptability, and preliminary efficacy among survivors of childhood cancer with chronic pain who were ≥ 18 years of age, able to speak and read English, lived in the United States, and had access to a smartphone and the Internet. The primary outcomes were pain interference, pain severity, anxiety, negative affect, and perceived stress. The intervention group (n = 32) received a wearable respiratory monitor, used the device, and completed an in-application breathing exercise daily for 30 days. The control group (n = 33) received psychoeducation after completion of the study.

resultsAlmost all participants in the intervention group (n = 31 of 32) and control group (n = 32 of 33) completed the study. Of those who completed the intervention, 90.3% wore the device for ≥ 50% of the trial. Posttreatment improvement for negative affect (Cohen

conclusionThe results of this pilot study support the acceptability and feasibility of wearable respiratory monitoring among survivors of childhood cancer. Larger randomized trials are needed to assess efficacy and maintenance of this intervention for chronic pain.

Indexed as

Cancer SurvivorsChronic PainNeoplasmsWearable Electronic DevicesAdultFeasibility StudiesFeedbackHumansSurvivors

Identifiers

PMID33147073
PMCPMC7713517
OpenAlexW3097472259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.