ArticleSocial psychiatry and psychiatric epidemiology2021
Paracetamol-related intentional drug overdose among young people: a national registry study of characteristics, incidence and trends, 2007-2018.
Article in Social psychiatry and psychiatric epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- A comprehensive overview of paracetamol poisoning admissions and long-term outcomes in New South Wales, Australia: a retrospective linked data cohort (PAVLOVA-3).The Lancet regional health. Western Pacific · 2026Article
- Experimental effects of paracetamol overdose on the development of forensic insects.Forensic science, medicine, and pathology · 2026Article
- Commonly available dietary supplements, herbs and medicines - do they pose a risk for liver health? Literature review in the context of the Polish population.Clinical and experimental hepatology · 2024Review
- Paracetamol overdose causing acute kidney injury without hepatotoxicity: a case report.International journal of emergency medicine · 2024Article
- Sentinel surveillance of substance-related self-harm in Canadian emergency departments, 2011 - 19.BMC public health · 2022Article
- Estimates of Paracetamol Poisoning in Brazil: Analysis of Official Records From 1990s to 2020.Frontiers in pharmacology · 2022Article
- The impact of guidance on the supply of codeine-containing products on their use in intentional drug overdose.European journal of public health · 2021Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIncidence rates of hospital-presenting self-harm are highest in people under 25 years and are reportedly increasing in some countries. Intentional drug overdose (IDO) is the most common self-harm method among young people, with paracetamol the drug most frequently used. This study aimed to describe the characteristics, incidence, and temporal trends in paracetamol-related IDO among young people.
methodsData from the National Self-Harm Registry Ireland on hospital-presenting self-harm by individuals aged 1024 years during 2007-2018 were examined. Annual IDO rates per 100,000 were calculated by age and gender. Joinpoint regression analyses and incidence rate ratios were used to examine trends in the incidence of paracetamol-related IDO.
resultsDuring the study, 10,985 paracetamol-related IDOs were recorded. The incidence of paracetamol-related IDO among young people increased by 9% between 2007 and 2018 (IRR 1.09 95% CI 1.00-1.19), with the highest annual percentage change (APC) in females aged 18-24 years (APC 1.2%). Conversely, rates of paracetamol-related IDO among males aged 18-24 years decreased significantly (APC 1.6%). Between 2013 and 2018, excesses of 386 and 151 paracetamol-related IDOs were observed in females aged 10-17 and 18-24 years, respectively, and 42 excess presentations were observed for males aged 10-17 years. There were 107 fewer presentations than expected for males aged 18-24 years.
conclusionThe increase in paracetamol-related IDO among specific groups of young people, particularly young females is an issue of growing concern. Interventions targeting IDO among young people are needed, incorporating measures to address the availability of paracetamol and aftercare following IDO.
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