ArticleEJNMMI physics2020
High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera.
Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy.European journal of nuclear medicine and molecular imaging · 2024Guideline
- Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade.International journal of molecular sciences · 2022Pooled it
- Comparison of Diagnostic Performance of Whole-Body 360° CZT Bone SPECT/CT and Planar Bone Scintigraphy in Detecting Bone Metastasis in Small Cell Lung Cancer.Diagnostics (Basel, Switzerland) · 2026Article
- Quantitative accuracy ofEJNMMI physics · 2026Article
- Analytical methods for system matrix calculation and spatial resolution evaluation of DC-SPECT system.Physics in medicine and biology · 2025Article
- The Image Clarity Paradox: Higher CZT SPECT Contrast Does Not Always Translate to Diagnostic Accuracy for Alzheimer's Disease.Tomography (Ann Arbor, Mich.) · 2025Article
- Comparative Assessment of Agreement in Uniformity Analyses across Quality Control Software Platforms.World journal of nuclear medicine · 2025Article
- Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT.Asia Oceania journal of nuclear medicine & biology · 2025Article
- Recent advances in radionuclide medical imaging techniques.Frontiers in medicine · 2025Review
- Diagnostic Ability of Quantitative Parameters of Whole-Body Bone SPECT/CT Using a Full-Ring 360° Cadmium-Zinc-Telluride Camera for Detecting Bone Metastasis in Patients with Prostate Cancer.Diagnostics (Basel, Switzerland) · 2024Article
- Bias and precision of SPECT-basedEJNMMI physics · 2024Article
- 360° CZT-SPECT/CT cameras:EJNMMI physics · 2024Article
- EANM perspectives for CZT SPECT in brain applications.European journal of nuclear medicine and molecular imaging · 2024Article
- Performance evaluation of the 3D-ring cadmium-zinc-telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard.EJNMMI physics · 2024Article
- Performance study of a 360° CZT camera for monitoringEJNMMI physics · 2023Article
- Identification of resting-state networks using dynamic brain perfusion SPECT imaging: A fSPECT case report.Frontiers in human neuroscience · 2023Article
- Molecular Imaging in Parkinsonian Disorders-What's New and Hot?Brain sciences · 2022Review
- Dopamine transporter (DAT) imaging in Parkinson's disease and related disorders.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- Relationship Between Vitamin D Status and Brain Perfusion in Neuropsychiatric Lupus.Nuclear medicine and molecular imaging · 2022Article
- EANM procedure guidelines for brain PET imaging using [European journal of nuclear medicine and molecular imaging · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare brain perfusion SPECT obtained from a 360° CZT and a conventional Anger camera.
methodsThe 360° CZT camera utilizing a brain configuration, with 12 detectors surrounding the head, was compared to a 2-head Anger camera for count sensitivity and image quality on 30-min SPECT recordings from a brain phantom and from
resultsThe CZT camera provided more than 2-fold increase in count sensitivity, as compared with the Anger camera, as well as (1) lower sharpness indexes, giving evidence of higher spatial resolution, for both peripheral/central brain structures, with respective median values of 5.2%/3.7% versus 2.4%/1.9% for CZT and Anger camera respectively in patients (p < 0.01), and 8.0%/6.9% versus 6.2%/3.7% on phantom; and (2) higher gray/white matter contrast on peripheral/central structures, with respective ratio median values of 1.56/1.35 versus 1.11/1.20 for CZT and Anger camera respectively in patients (p < 0.05), and 2.57/2.17 versus 1.40/1.12 on phantom; and (3) no change in noise level. Image quality, scored visually by experienced physicians, was also significantly higher on CZT than on the Anger camera (+ 80%, p < 0.01), and all these results were unchanged on the CZT images obtained with only a 15 min recording time.
conclusionThe 360° CZT camera provides brain perfusion images of much higher quality than a conventional Anger camera, even with high-speed recordings, thus demonstrating the potential for repositioning brain perfusion SPECT to the forefront of brain imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.