Evidence map›Paper›PMID 33146771›Full record

ReviewJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2020

Critical discussion of the applications of metal complexes for 2-photon photodynamic therapy.

Johannes Karges, Hui Chao, Gilles Gasser

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes.Journal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Johannes KargesDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. jkarges@ucsd.edu.ORCID http://orcid.org/0000-0001-5258-0260
Hui ChaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China. ceschh@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-4153-5303
Gilles GasserLaboratory for Inorganic Chemical Biology, Institute of Chemistry for Life and Health Sciences, Chimie ParisTech, PSL University, CNRS, 75005, Paris, France. gilles.gasser@chimieparistech.psl.eu.ORCID http://orcid.org/0000-0002-4244-5097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy is a light-activated medical technique, which has received increasing attention within the last decade to treat various diseases including bacterial, viral or fungal infections as well as cancer. To overcome the limitations of the currently clinically applied photosensitizers based on a tetrapyrrolic scaffold, metal complexes are sought to be an interesting alternative. While these complexes show attractive photophysical and biological properties, the majority of these compounds are excited using visible light, which is associated with a poor tissue penetration. To circumvent this drawback, increasing attention has been devoted towards the use of 2-Photon instead of 1-Photon irradiation. In this mini-review, the metal complexes prepared in view of 2P-PDT are reviewed and the requirements these compounds need to fulfil to be of interest are critically discussed.

Indexed as

Coordination ComplexesPhotonsHumansPhotochemotherapyCoordination ComplexesBioinorganic chemistryMedicinal inorganic chemistryMetals in medicinePhotodynamic therapyPhotosensitizers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.