Evidence map›Paper›PMID 33146611›Full record

ArticleeLife2020

Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis.

Sara Alvira, Daniel W Watkins, Luca Troman, William J Allen, James S Lorriman, Gianluca Degliesposti, Eli J Cohen, Morgan Beeby, Bertram Daum, Vicki Am Gold and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Cracking outer membrane biogenesis.Biochimica et biophysica acta. Molecular cell research · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sara Alvira *School of Biochemistry, University of Bristol, Bristol, United Kingdom.
Daniel W Watkins *School of Biochemistry, University of Bristol, Bristol, United Kingdom.ORCID 0000-0003-3825-5036
Luca TromanSchool of Biochemistry, University of Bristol, Bristol, United Kingdom.
William J AllenSchool of Biochemistry, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-9513-4786
James S LorrimanSchool of Biochemistry, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-1755-0805
Gianluca DegliespostiBiological Mass Spectrometry and Proteomics, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Eli J CohenDepartment of Life Sciences, Imperial College London, London, United Kingdom.
Morgan BeebyDepartment of Life Sciences, Imperial College London, London, United Kingdom.ORCID 0000-0001-6413-9835
Bertram DaumLiving Systems Institute, University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-3767-264X
Vicki Am GoldLiving Systems Institute, University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-6908-0745
J Mark SkehelBiological Mass Spectrometry and Proteomics, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Ian CollinsonSchool of Biochemistry, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-3931-0503
University of Bristol · GBImperial College London · GBMRC Laboratory of Molecular Biology · GBUniversity of Exeter · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J014400/1Biotechnology and Biological Sciences Research Council BB/M003604/1Biotechnology and Biological Sciences Research Council BB/M009122/1Biotechnology and Biological Sciences Research Council BB/N015126/1Biotechnology and Biological Sciences Research Council BB/R000484/1Biotechnology and Biological Sciences Research Council BB/S008349/1Medical Research Council MC_U105184326Wellcome Trust
6 · The paper itself

Abstract

The outer-membrane of Gram-negative bacteria is critical for surface adhesion, pathogenicity, antibiotic resistance and survival. The major constituent - hydrophobic β-barrel

Indexed as

Gene Expression Regulation, BacterialBacterial Outer Membrane ProteinsBacterial Secretion SystemsEscherichia coliModels, MolecularProtein ConformationProtein TransportBacterial Outer Membrane ProteinsBacterial Secretion SystemsBAM complexbiochemistrychemical biologyE. coliholotransloconHTL-BAMouter membrane proteinsec complexSecYEG

Identifiers

PMID33146611
PMCPMC7695460
OpenAlexW3095821357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.