Evidence map›Paper›PMID 33146553›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2021

Bladder underactivity induced by prolonged pudendal afferent activity in cats.

Anand Mohapatra, Jialiang Chen, Jun Zhao, Yihua Zhong, Kody Armann, Bing Shen, Jicheng Wang, Jonathan Beckel, William C de Groat, Changfeng Tai

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Sacral neuromodulation of bladder underactivity induced by prolonged pudendal afferent firing in cats.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  4. Superficial peroneal neuromodulation of nonobstructive urinary retention induced by prolonged pudendal afferent activity in cats.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  5. Mechanism of Action of Peripheral Nerve Stimulation.Current pain and headache reports · 2021
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Anand MohapatraDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jialiang ChenDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jun ZhaoDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yihua ZhongDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Kody ArmannDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Bing ShenDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jicheng WangDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jonathan BeckelDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
William C de GroatDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Changfeng TaiDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USCapital Medical University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNSun Yat-sen University · CN

Funding

Parasympathetic and sympathetic mechanisms underlying bladder nociceptionR01DK111382 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKEL, JONATHAN M · 2017 to 2020
$1.4M
Neuromodulation for Non-Obstructive Urinary Retention (NOUR)R01DK121698 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAI, CHANGFENG · 2019 to 2021
$704k
NIDDK NIH HHS R01 DK111382NIDDK NIH HHS R01 DK121698
6 · The paper itself

Abstract

The purpose of this study was to determine the effects of pudendal nerve stimulation (PNS) on reflex bladder activity and develop an animal model of underactive bladder (UAB). In six anesthetized cats, a bladder catheter was inserted via the urethra to infuse saline and measure pressure. A cuff electrode was implanted on the pudendal nerve. After determination of the threshold intensity (T) for PNS to induce an anal twitch, PNS (5 Hz, 0.2 ms, 2 T or 4 T) was applied during cystometrograms (CMGs). PNS (4-6 T) of 30-min duration was then applied repeatedly until bladder underactivity was produced. Following stimulation, control CMGs were performed over 1.5-2 h to determine the duration of bladder underactivity. When applied during CMGs, PNS (2 T and 4 T) significantly (

Indexed as

Electric StimulationReflexUrodynamicsAnimalsCatsDisease Models, AnimalFemaleMalePudendal NerveTime FactorsUrethraUrinary BladderUrinary Bladder, Underactivebladdercatpudendalstimulationunderactivity

Identifiers

PMID33146553
PMCPMC7847056
OpenAlexW3097265828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.