Evidence map›Paper›PMID 33146155›Full record

ArticleThe Indian journal of medical research

Modelling the spread of SARS-CoV-2 pandemic - Impact of lockdowns & interventions.

Manindra Agrawal, Madhuri Kanitkar, M Vidyasagar

Open access · diamondAbstract read
In one paragraph

Article in The Indian journal of medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Effectiveness of social distancing measures and lockdowns for reducing transmission of COVID-19 in non-healthcare, community-based settings.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The making of India's COVID-19 disaster: A Disaster Risk Management (DRM) Assemblage analysis.International journal of disaster risk reduction : IJDRR · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. COVID-19 Pandemic in India: Through the Lens of Modeling.Global health, science and practice · 2021
    Article
  12. Article
  13. Universal Epidemic Curve for COVID-19 and Its Usage for Forecasting.Transactions of the Indian National Academy of Engineering : an international journal of engineering and technology · 2021
    Article
  14. Pandemics, COVID-19 and India.Indian economic review · 2020
    Article
  15. Authors' response.The Indian journal of medical research
    Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Manindra AgrawalDepartment of Computer Science & Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.
Madhuri KanitkarDeputy Chief Integrated Defence Staff (Medical), HQ Integrated Defense Staff, Ministry of Defence, Government of India, New Delhi, India.
M VidyasagarDepartment of Artificial Intelligence, Indian Institute of Technology Hyderabad, Hyderabad, Telangana, India.
Government of India · INIndian Institute of Technology Hyderabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

objectivesTo handle the current COVID-19 pandemic in India, multiple strategies have been applied and implemented to slow down the virus transmission. These included clinical management of active cases, rapid development of treatment strategies, vaccines computational modelling and statistical tools to name a few. This article presents a mathematical model for a time series prediction and analyzes the impact of the lockdown.

methodsSeveral existing mathematical models were not able to account for asymptomatic patients, with limited testing capability at onset and no data on serosurveillance. In this study, a new model was used which was developed on lines of susceptible-asymptomatic-infected-recovered (SAIR) to assess the impact of the lockdown and make predictions on its future course. Four parameters were used, namely β, γ, η and ε. β measures the likelihood of the susceptible person getting infected, and γ denotes recovery rate of patients. The ratio β/γ is denoted by R

resultsThe disease spread was reduced due to initial lockdown. An increase in γ reflects healthcare and hospital services, medications and protocols put in place. In Delhi, the predictions from the model were corroborated with July and September serosurveys, which showed antibodies in 23.5 and 33 per cent population, respectively. INTERPRETATION &

conclusionsThe SAIR model has helped understand the disease better. If the model is correct, we may have reached herd immunity with about 380 million people already infected. However, personal protective measures remain crucial. If there was no lockdown, the number of active infections would have peaked at close to 14.7 million, resulted in more than 2.6 million deaths, and the peak would have arrived by June 2020. The number of deaths with the current trends may be less than 0.2 million.

Indexed as

Communicable Disease ControlModels, TheoreticalPandemicsAntibodies, ViralCOVID-19HumansIndiaAntibodies, ViralAsymptomatic casesIndialockdownmodellingresources

Identifiers

PMID33146155
PMCPMC8184064
OpenAlexW3095436644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.