Evidence map›Paper›PMID 33145962›Full record

ArticleJournal of cellular and molecular medicine2020

Dynamics of NK, CD8 and Tfh cell mediated the production of cytokines and antiviral antibodies in Chinese patients with moderate COVID-19.

Lin Yan, Bei Cai, Yi Li, Min-Jin Wang, Yun-Fei An, Rong Deng, Dong-Dong Li, Li-Chun Wang, Huan Xu, Xue-Dan Gao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Review
  7. Immune Checkpoint Molecules Expressed on CD4Frontiers in microbiology · 2022
    Article
  8. Article
  9. The Ratio of CD226 and TIGIT Expression in Tfh and PD-1Journal of immunology research · 2022
    Article
  10. Review
  11. Innate lymphoid cells (ILC) in SARS-CoV-2 infection.Molecular aspects of medicine · 2021
    Review
  12. Alterations in the Composition of Intestinal DNA Virome in Patients With COVID-19.Frontiers in cellular and infection microbiology · 2021
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lin YanDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Bei CaiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Yi LiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Min-Jin WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Yun-Fei AnDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Rong DengCenter of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
Dong-Dong LiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Li-Chun WangCenter of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
Huan XuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Xue-Dan GaoDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Lan-Lan WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-0601-1275
Sichuan University · CN

Funding

1•3•5 Project for Disciplines of Excellence, West China Hospital, Sichuan University ZYJC18004Chengdu Technology Innovation Research and Development Project 2020-YF05-0026-SNKey Research and Development Project of Department of Science and Technology of Sichuan Province 2020YFS0228National Natural Science Foundation 81771714National Natural Science Foundation 81871713
6 · The paper itself

Abstract

Recent studies have demonstrated a marked decrease in peripheral lymphocyte levels in patients with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Few studies have focused on the changes of NK, T- and B-cell subsets, inflammatory cytokines and virus-specific antibodies in patients with moderate COVID-19. A total of 11 RT-PCR-confirmed convalescent patients with COVID-19 and 11 patients with non-SARS-CoV-2 pneumonia (control patients) were enrolled in this study. NK, CD8

Indexed as

AdultAgedAntibodies, ViralCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesChinaCOVID-19CytokinesFemaleHumansKiller Cells, NaturalMaleMiddle AgedSARS-CoV-2T Follicular Helper CellsYoung AdultAntibodies, ViralCytokinesCD8COVID-19NKTfhTIM-3

Identifiers

PMID33145962
PMCPMC7753779
OpenAlexW3097387441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.