Evidence map›Paper›PMID 33145738›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022

Simultaneous assessment of microcalcifications and morphological criteria of vulnerability in carotid artery plaque using hybrid

Laura Mechtouff, Monica Sigovan, Philippe Douek, Nicolas Costes, Didier Le Bars, Adeline Mansuy, Julie Haesebaert, Alexandre Bani-Sadr, Jérémie Tordo, Patrick Feugier and 11 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02726984 (Assessment of Symptomatic and Asymptomatic Carotid Plaques Using Hybrid Imaging 18F-sodium Fluoride PET/MR), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02726984 nacompletednot on this map

Assessment of Symptomatic and Asymptomatic Carotid Plaques Using Hybrid Imaging 18F-sodium Fluoride PET/MR

TypeinterventionalSponsorHospices Civils de LyonRan2016 to 2017Enrolled15ConditionsCarotid Artery PlaqueArms18F-sodium fluoride PET/MR
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Vascular medicine (London, England) · 2025
    Pooled it
  2. Review
  3. Article
  4. Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024
    Review
  5. Review
  6. Radiology · 2022
    Observational
  7. Scientific reports · 2021
    Article
  8. Review
  9. Review
  10. The Elusive Origin of Atherosclerotic Plaque Calcification.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 1 country.

Laura MechtouffStroke Department, Pierre Wertheimer Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69677, Bron, France. laura.mechtouff@chu-lyon.fr.
Monica SigovanCNRS, UMR 5220, CREATIS, University of Lyon, Lyon, France.
Philippe DouekCNRS, UMR 5220, CREATIS, University of Lyon, Lyon, France.
Nicolas CostesCERMEP - Imagerie du vivant, Lyon, France.
Didier Le BarsCERMEP - Imagerie du vivant, Lyon, France.
Adeline MansuyCellule Recherche Imagerie, Louis Pradel University Hospital, Bron, France.
Julie HaesebaertClinical Research and Epidemiology Unit, Public Health Department Hospices Civils de Lyon & Université de Lyon, Université Claude Bernard Lyon 1, Université Saint-Étienne, HESPER EA 7425, F-69008 Lyon, 42023, Saint-Etienne, France.
Alexandre Bani-SadrDepartment of Nuclear Medicine, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France.
Jérémie TordoDepartment of Nuclear Medicine, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France.
Patrick FeugierVascular Surgery Department, Edouard Herriot University Hospital & Claude Bernard Lyon 1 University, Lyon, France.
Antoine MillonVascular Surgery Department, Edouard Herriot University Hospital & Claude Bernard Lyon 1 University, Lyon, France.
Stéphane LuongDepartment of Radiology, Louis Pradel University Hospital, Bron, France.
Salim Si-MohamedDepartment of Radiology, Louis Pradel University Hospital, Bron, France.
Diane Collet-BenzaquenLaboratoire d'Anatomie et de Cytologie pathologiques Technipath, Limonest, France.
Emmanuelle Canet-SoulasINSERM U1060, CarMeN Laboratory, University Lyon 1, Lyon, France.
Thomas BochatonINSERM U1060, CarMeN Laboratory, University Lyon 1, Lyon, France.
Claire Crola Da SilvaINSERM U1060, CarMeN Laboratory, University Lyon 1, Lyon, France.
Alexandre PaccaletINSERM U1060, CarMeN Laboratory, University Lyon 1, Lyon, France.
David MagneICBMS, CNRS, UMR 5246, University Lyon 1, Lyon, France.
Yves BerthezeneCNRS, UMR 5220, CREATIS, University of Lyon, Lyon, France.
Norbert NighoghossianStroke Department, Pierre Wertheimer Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69677, Bron, France.
Université Claude Bernard Lyon 1 · FRHospices Civils de Lyon · FRInserm · FRHôpital Louis Pradel · FRCentre d'Exploration et de Recherche Médicale par Emission de Positons · FRHôpital Pierre Wertheimer · FRInstitut National des Sciences Appliquées de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have suggested the role of microcalcifications in plaque vulnerability. This exploratory study sought to assess the potential of hybrid positron-emission tomography (PET)/magnetic resonance imaging (MRI) using METHODS AND

resultsWe included 12 patients with either recently symptomatic or asymptomatic carotid stenosis. All patients underwent

conclusions

Indexed as

CalcinosisCarotid StenosisPlaque, AtheroscleroticHumansMagnetic Resonance ImagingPositron-Emission TomographySodium FluorideSodium FluorideCarotid stenosisHybrid MR/PETPositron-Emission Tomography-Computed TomographySodium FluorideStroke

Identifiers

PMID33145738
OpenAlexW3095756101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.